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Molecules 2016, 21(3), 292;

Modified Polyacrylic Acid-Zinc Composites: Synthesis, Characterization and Biological Activity

Department of Chemistry, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 6 January 2016 / Revised: 13 February 2016 / Accepted: 25 February 2016 / Published: 29 February 2016
(This article belongs to the Section Bioorganic Chemistry)
Full-Text   |   PDF [4599 KB, uploaded 29 February 2016]   |  


Polyacrylic acid (PAA) is an important industrial chemical, which has been extensively applied in various fields, including for several biomedical purposes. In this study, we report the synthesis and modification of this polymer with various phenol imides, such as succinimide, phthalimide and 1,8-naphthalimide. The as-synthesized derivatives were used to prepare polymer metal composites by the reaction with Zn+2. These composites were characterized by using various techniques, including NMR, FT-IR, TGA, SEM and DSC. The as-prepared PAA-based composites were further evaluated for their anti-microbial properties against various pathogens, which include both Gram-positive and Gram-negative bacteria and different fungal strains. The synthesized composites have displayed considerable biocidal properties, ranging from mild to moderate activities against different strains tested. View Full-Text
Keywords: polyacrylic acid; zinc; metal composite; biological activity polyacrylic acid; zinc; metal composite; biological activity

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Shaik, M.R.; Kuniyil, M.; Khan, M.; Ahmad, N.; Al-Warthan, A.; Siddiqui, M.R.H.; Adil, S.F. Modified Polyacrylic Acid-Zinc Composites: Synthesis, Characterization and Biological Activity. Molecules 2016, 21, 292.

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