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Molecules 2014, 19(7), 9712-9735;

Synthesis and Photophysical Properties of the 2-(3-(2-Alkyl-6,8-diaryl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)propyl)-6,8-diarylquinazolin-4(3H)-ones

Department of Chemistry, College of Science, Engineering and Technology, University of South Africa, P.O. Box 392, Pretoria 0003, South Africa
Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh 33516, Egypt
Chemistry Department, Faculty of Science, El-Menoufia University, Shebin El-Kom 32512, Egypt
Graduate School of Information Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
Author to whom correspondence should be addressed.
Received: 6 June 2014 / Revised: 30 June 2014 / Accepted: 1 July 2014 / Published: 8 July 2014
(This article belongs to the Section Organic Chemistry)
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Iodine-catalyzed condensation of 2-amino-3,5-dibromobenzamide with cyclohexane-1,3-dione derivatives in refluxing toluene afforded the corresponding bisquinazolinones. Suzuki-Miyaura cross-coupling of the latter with arylboronic acids afforded tetraarylbisquinazolinones. The electronic absorption and emission properties of these tetraarylbisquinazolinones were measured in dimethylsulfoxide (DMSO) and acetic acid by means of UV-Vis and fluorescence spectroscopic techniques in conjunction with quantum chemical methods to understand the influence of substituents on intramolecular charge transfer (ICT). View Full-Text
Keywords: tetrabromobisquinazolinones; Suzuki-Miyaura cross-coupling; tetraarylbisquinazolinones; photophysical properties tetrabromobisquinazolinones; Suzuki-Miyaura cross-coupling; tetraarylbisquinazolinones; photophysical properties

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Mmonwa, M.M.; Mphahlele, M.J.; El-Hendawy, M.M.; El-Nahas, A.M.; Koga, N. Synthesis and Photophysical Properties of the 2-(3-(2-Alkyl-6,8-diaryl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)propyl)-6,8-diarylquinazolin-4(3H)-ones. Molecules 2014, 19, 9712-9735.

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