Molecules 2011, 16(11), 9739-9754; https://doi.org/10.3390/molecules16119739
Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities
Marine College, Shandong University, Weihai Wenhua West Road, No.180, Weihai 264209, China
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Received: 3 October 2011 / Revised: 9 November 2011 / Accepted: 14 November 2011 / Published: 23 November 2011
(This article belongs to the Section Medicinal Chemistry)
Abstract
A series of new substituted benzophenone derivatives was designed, synthesized and screened for their antifungal and antibacterial activities. The bioassays indicated that most of the synthesized compounds showed some antifungal activity against the tested phytopathogenic fungi, but lower antibacterial activities towards the five vibrios isolated from marine sources. The preliminary structure activity relationship (SAR) of the compounds was also discussed. View Full-TextKeywords:
benzophenone derivatives; bioactivity; phytopathogenic fungi; vibrio
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Sun, L.; Wu, J.; Luo, M.; Wang, X.; Pan, M.; Gou, Z.; Sun, D. Diversity Oriented Design of Various Benzophenone Derivatives and Their in Vitro Antifungal and Antibacterial Activities. Molecules 2011, 16, 9739-9754.
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