Microbiology Metabolomics

Dear Colleagues,

Omics technologies such as genomics, transcriptomics, proteomics, and metabolomics are extensively used for the identification and characterization of new molecular signatures. The significance of the metabolome is further underlined by its competence in manipulating the genome, transcriptome, and proteome. To better understand the roles of genes in biological systems, bioscience adopts metabolomic profiling, which provides detailed metabolic activities within the cell. The analysis of the metabolome provides deeper insight into cellular physiology and critical qualitative and quantitative information that help to understand related metabolic pathways and their alterations. Microbial metabolomics in intestinal flora provides an understanding of host interaction, host health, and disease status, while metabolome profiling of infective microbe offers information related to the diagnosis of the disease. Microbial metabolomics has often been used in food and nutrition to assess the impact of nutrient deficiency. Further, the dynamic microbial metabolome also provides information about microbial adaptation as well as the impact of environmental changes. Mass-spectrometry-based metabolomics analyses have made significant contributions to microbial metabolomics research in the environment and human disease. The aim of this Topic entitled “Microbiology Metabolomics” is to provide targeted and untargeted microbial metabolome profiles of the gut microbiome, pathogenic microbes, microbial metabolome associated with food and nutrition, and microbial metabolome describing the impact of environmental changes on metabolites and metabolic pathways. This Topic will consider original articles, commentaries, and review articles.

Dr. Sunil S. Adav
Prof. Dr. Gilles Comte
Topic Editors