Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine

Dear Colleagues,

Modern medicine is going through an extremely important moment in its evolution in relation to the disease–drug–patient axis, gradually progressing from pure drug development, which initiates from the need to prevent or treat certain diseases, to the expansion of coherent therapeutic strategies which are personalized for each individual, in recognition of the fact that each patient is a distinct physio-pathological case. Remarkable advances in recent decades in the prevention strategies, diagnostic procedures and available treatments have paved the way to major improvements in patient care. Personalized medicine is approachable if comprehensive details are known about the pathogenesis; the therapeutic agents developed for the management of the pathology in question; the biochemical mechanisms of action of the drugs; the interactions of the drugs with each other and with other endogenous or exogenous factors; and the genetic and epigenetic background of the patient, their chronobiological, nutritional and socio-demographic characteristics.

In this framework, the aim of this Special Issue on “Emerging strategies in drug development and clinical care in the era of personalized and precision medicine” is to unify the most relevant papers addressing the state-of-the-art knowledge and future directions in drug development, therapeutic strategies, and innovative drug formulations, with a focus on biochemical mechanisms of action and drug design, as well as the relevant preclinical and clinical testing of efficacy, pharmacokinetics and toxicity in the era of precision and personalized medicine.

We welcome articles dealing with all aspects of pharmaceutical and medical care, from basic to clinical research, and invite scientists and drug specialists to publish their original research works, review articles, and communications on this wide health domain.

Dr. Cristina Manuela Drăgoi 
Dr. Alina Crenguța Nicolae
Dr. Ion-Bogdan Dumitrescu
Guest Editors

Manuscript Submission Information

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