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14 Results Found

  • Article
  • Open Access
9 Citations
10,903 Views
18 Pages

Structural, Thermoanalytical and Molecular Modeling Studies on N-(3-hydroxypropyl) 3α,12α-Dihydroxy-5β-cholan-24-amide and Its Monohydrates

  • Arto Valkonen,
  • Erkki Kolehmainen,
  • Manu Lahtinen,
  • Elina Sievänen,
  • Virpi Noponen,
  • Minna Tolonen and
  • Reijo Kauppinen

12 September 2007

The synthetic method for preparing N-(3-hydroxypropyl) 3α,12α-dihydroxy-5β- cholan-24-amide can lead to formation of at least three different crystal forms – an anhydrous compound and two monohydrates. The structural and thermal properties of these f...

  • Article
  • Open Access
16 Citations
3,103 Views
13 Pages

Single-Cellular Biological Effects of Cholesterol-Catabolic Bile Acid-Based Nano/Micro Capsules as Anti-Inflammatory Cell Protective Systems

  • Armin Mooranian,
  • Corina Mihaela Ionescu,
  • Daniel Walker,
  • Melissa Jones,
  • Susbin Raj Wagle,
  • Bozica Kovacevic,
  • Jacqueline Chester,
  • Thomas Foster,
  • Edan Johnston and
  • Jafri Kuthubutheen
  • + 4 authors

4 January 2022

Recent studies in our laboratories have shown promising effects of bile acids in ➀ drug encapsulation for oral targeted delivery (via capsule stabilization) particularly when encapsulated with Eudragit NM30D® and ➁ viable-cell encap...

  • Article
  • Open Access
5 Citations
2,324 Views
14 Pages

Effects of 405 ± 5-nm LED Illumination on Environmental Stress Tolerance of Salmonella Typhimurium in Sliced Beef

  • Du Guo,
  • Yichen Bai,
  • Shengyi Fei,
  • Yanpeng Yang,
  • Jiahui Li,
  • Baowei Yang,
  • Xin Lü,
  • Xiaodong Xia and
  • Chao Shi

6 January 2022

Salmonella Typhimurium is a widely distributed foodborne pathogen and is tolerant of various environmental conditions. It can cause intestinal fever, gastroenteritis and bacteremia. The aim of this research was to explore the effect of illumination w...

  • Article
  • Open Access
20 Citations
5,560 Views
22 Pages

10 August 2022

Nattokinase is a potential new thrombolytic drug because of its strong thrombolytic effect, high safety, and low cost. However, there is no research reporting on bile salt-tolerant nattokinase-producing probiotics. In this study, the bile salt-tolera...

  • Article
  • Open Access
30 Citations
3,519 Views
18 Pages

6 July 2022

The influence of different extraction methods, such as acidic (AC), enzymatic (EN), homogenization (H), ultrsonication (U) and alkali (AL), on structure, rheological, thermal and functional properties of soluble dietary fiber (SDF) from Sanchi flower...

  • Article
  • Open Access
1 Citations
2,948 Views
24 Pages

The search for natural antimicrobials has intensified with rising food safety demands. This study evaluated 23 probiotic strains, identifying Bifidobacterium sp. strain TF04 as a potent inhibitor against pathogens, with inhibition zone diameters of 1...

  • Article
  • Open Access
8 Citations
3,983 Views
19 Pages

Quantitative Lipidome Analysis of Boiled Chicken Egg Yolk under Different Heating Intensities

  • Wei Luo,
  • Jinghui Wang,
  • Yan Chen,
  • Qionglian Zhang,
  • Jinqiu Wang and
  • Fang Geng

The effects of the four heating intensities (hot-spring egg yolk, HEY; soft-boiled egg yolk, SEY; normal-boiled egg yolk, NEY; and over-boiled egg yolk, OEY) on lipidomes of boiled egg yolks were investigated. The results indicated that four heating...

  • Article
  • Open Access
3 Citations
1,975 Views
17 Pages

14 October 2024

In this research, the dietary fibers (DFs) from ginseng residue were extracted by employing three different extraction methods (alkaline: AL, acidic: AC, enzymatic: EN). The extracted DFs were characterized in terms of their structural and functional...

  • Article
  • Open Access
5 Citations
2,556 Views
10 Pages

Enzymatic Synthesis of New Acetoacetate–Ursodeoxycholic Acid Hybrids as Potential Therapeutic Agents and Useful Synthetic Scaffolds as Well

  • Valentina Venturi,
  • Elena Marchesi,
  • Daniela Perrone,
  • Valentina Costa,
  • Martina Catani,
  • Simona Aprile,
  • Lindomar Alberto Lerin,
  • Federico Zappaterra,
  • Pier Paolo Giovannini and
  • Lorenzo Preti

15 March 2024

Ursodeoxycholic acid (UDCA) and acetoacetate are natural compounds present in the human intestine and blood, respectively. A number of studies highlighted that besides their well-known primary biological roles, both compounds possess the ability to i...

  • Article
  • Open Access
22 Citations
4,500 Views
16 Pages

Small Molecule Inhibitors of the Response Regulator ArsR Exhibit Bactericidal Activity against Helicobacter pylori

  • Andrés González,
  • Javier Casado,
  • Eduardo Chueca,
  • Sandra Salillas,
  • Adrián Velázquez-Campoy,
  • Javier Sancho and
  • Ángel Lanas

Helicobacter pylori is considered the most prevalent bacterial pathogen in humans. The increasing antibiotic resistance evolved by this microorganism has raised alarm bells worldwide due to the significant reduction in the eradication rates of tradit...

  • Article
  • Open Access
21 Citations
2,998 Views
12 Pages

Modified Potentiometric Screen-Printed Electrodes Based on Imprinting Character for Sodium Deoxycholate Determination

  • Ayman H. Kamel,
  • Samar Ezzat,
  • Mona A. Ahmed,
  • Abd El-Galil E. Amr,
  • Abdulrahman A. Almehizia and
  • Mohamed A. Al-Omar

6 February 2020

Potentiometric sensors have a great influence on the determination of most various compounds in their matrices. Therefore, efficient and new sensors were introduced to measure sodium Deoxycholate (NaDC) as a bile acid salt. These sensors are based on...

  • Article
  • Open Access
17 Citations
5,448 Views
16 Pages

Role of TRP Channels in Shaping the Gut Microbiome

  • Ravinder Nagpal,
  • Santosh Kumar Mishra,
  • Gagan Deep and
  • Hariom Yadav

16 September 2020

Transient receptor potential (TRP) channel family proteins are sensors for pain, which sense a variety of thermal and noxious chemicals. Sensory neurons innervating the gut abundantly express TRPA1 and TRPV1 channels and are in close proximity of gut...

  • Article
  • Open Access
25 Citations
6,357 Views
15 Pages

Physicochemical and Functional Characteristics of RD43 Rice Flour and Its Food Application

  • Phim on Suklaew,
  • Charoonsri Chusak and
  • Sirichai Adisakwattana

21 December 2020

The increased use of a new rice cultivar is the result of increasing consumer demands for healthier choices. In this study, physicochemical, thermal, pasting, and functional properties of flour from RD43 rice, a new rice variety, and its food applica...

  • Abstract
  • Open Access
1 Citations
1,352 Views
2 Pages

Colonic Fermentation of Coffee Melanoidins and Resulting Cardioprotective Metabolites

  • Fernanda Machado,
  • Irene Gómez-Domínguez,
  • Raul Hurtado-Ribeira,
  • Diana Martin,
  • Manuel A. Coimbra,
  • María Dolores del Castillo and
  • Filipe Coreta-Gomes

14 August 2023

Worldwide, noncommunicable diseases accounted for 7 out of 10 deaths in 2019 (WHO), being ischemic heart disease one of the major contributors. Coffee has been implicated with several health benefits, namely the hypocholesterolemic potential, attribu...