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8 Results Found

  • Article
  • Open Access
5 Citations
3,104 Views
12 Pages

S-Nitrosylation of Paraxonase 1 (PON1) Elevates Its Hydrolytic and Antioxidant Activities

  • Hanin Hajouj,
  • Ali Khattib,
  • Dana Atrahimovich,
  • Sanaa Musa and
  • Soliman Khatib

7 March 2022

Covalent binding between nitric oxide (NO) and a protein’s free thiol group (SH) is termed protein S-nitrosylation. Protein S-nitrosylation is involved in cellular regulation mechanisms that underlie a wide range of critical functions, such as...

  • Feature Paper
  • Article
  • Open Access
11 Citations
4,356 Views
15 Pages

Interactions of Paraoxonase-1 with Pharmacologically Relevant Carbamates

  • Anita Bosak,
  • Aljoša Bavec,
  • Tilen Konte,
  • Goran Šinko,
  • Zrinka Kovarik and
  • Marko Goličnik

4 January 2020

Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a...

  • Article
  • Open Access
11 Citations
3,200 Views
18 Pages

19 October 2022

Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities. Scientists are currently focused on the modulation of PON1 expression...

  • Review
  • Open Access
7 Citations
5,539 Views
22 Pages

28 January 2022

The primary olfactory system (POS) is in permanent renewal, especially the primary olfactory neurons (PON) are renewed with a turnover of around four weeks, even in adulthood. The re-growth of these axons is helped by a specific population of glial c...

  • Article
  • Open Access
41 Citations
15,316 Views
14 Pages

Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients

  • María Benlloch,
  • María Mar López-Rodríguez,
  • María Cuerda-Ballester,
  • Eraci Drehmer,
  • Sandra Carrera,
  • Jose Joaquin Ceron,
  • Asta Tvarijonaviciute,
  • Javier Chirivella,
  • David Fernández-García and
  • Jose Enrique de la Rubia Ortí

23 May 2019

Background: It was previously established that Multiple sclerosis (MS) generates energy alterations at the mitochondrial level related to the loss of muscle mass. Ketone bodies, mainly beta-hydroxybutyrate (BHB), re-establish this energy alteration c...

  • Article
  • Open Access
3 Citations
5,237 Views
21 Pages

17 July 2022

Current mass balances of C, N, and P were estimated using a model (Fluxin = Fluxout + ΔFlux) from Gamak Bay, Korea, in August 2017, where eutrophication and reducing conditions are prevalent. To examine the current fluxes of particulate organic...

  • Article
  • Open Access
9 Citations
3,049 Views
23 Pages

A Real-Life Application of a Smart User Network

  • Giuseppe Barone,
  • Giovanni Brusco,
  • Alessandro Burgio,
  • Daniele Menniti,
  • Anna Pinnarelli,
  • Michele Motta,
  • Nicola Sorrentino and
  • Pasquale Vizza

15 December 2018

Smart Community microgrids could help to improve overall energy efficiency reducing transmission and distribution losses and allowing the implementation of optimal load control and resource dispatching. In this context, the authors have proposed the...

  • Article
  • Open Access
1 Citations
1,957 Views
19 Pages

Hepatic macrophages act as the liver’s first line of defense against injury. Their differentiation into proinflammatory or anti-inflammatory subpopulations is a critical event that maintains a delicate balance between liver injury and repair. I...