You are currently on the new version of our website. Access the old version .

25 Results Found

  • Review
  • Open Access
1 Citations
3,644 Views
19 Pages

The Challenges of Diagnosing, Managing, and Preventing Pediatric Delirium

  • Juliana Patrícia Chaves de Almeida,
  • Yu Kawai,
  • Arnaldo Prata-Barbosa and
  • Roberta Esteves Vieira de Castro

11 July 2025

Pediatric delirium (PD) is an acute neuropsychiatric syndrome marked by fluctuating disturbances in attention and cognition, frequently observed in pediatric intensive care units (PICUs) and associated with increased morbidity, mortality, and long-te...

  • Article
  • Open Access
4 Citations
2,452 Views
17 Pages

Challenges of the Implementation of a Delirium Rate Scale in a Pediatric Intensive Care Unit: A Qualitative Approach

  • Paula Balsalobre-Martínez,
  • Raquel Montosa-García,
  • Ana Marín-Yago,
  • Manuel Baeza-Mirete,
  • Gloria María Muñoz-Rubio and
  • Andrés Rojo-Rojo

26 December 2023

Introduction: Delirium in the pediatric population admitted to intensive care is a worrying reality due to its potential complications and the increase in associated costs. This study aims to explore the experiences of nursing staff of a Pediatric In...

  • Article
  • Open Access
21 Citations
5,312 Views
10 Pages

Incidence of Emergence Delirium in the Pediatric PACU: Prospective Observational Trial

  • Eva Klabusayová,
  • Tereza Musilová,
  • Dominik Fabián,
  • Tamara Skříšovská,
  • Václav Vafek,
  • Martina Kosinová,
  • Michaela Ťoukálková,
  • Adéla Vrtková,
  • Jozef Klučka and
  • Petr Štourač

21 October 2022

Emergence delirium (ED) is a postoperative complication in pediatric anesthesia characterized by perception and psychomotor disorder and has a negative impact on morbidity in the form of maladaptive behavior, which can last weeks after anesthesia. Pa...

  • Article
  • Open Access
1,536 Views
12 Pages

Verifying the Japanese Version of Pediatric Delirium and Withdrawal Syndrome Assessment Scale: SOS-PD Validation Study for Iatrogenic Withdrawal Syndrome

  • Yujiro Matsuishi,
  • Haruhiko Hoshino,
  • Yuki Enomoto,
  • Takahiro Kido,
  • Nobutake Shimojo,
  • Bryan J. Mathis,
  • Erwin Ista and
  • Yoshiaki Inoue

17 March 2025

Background: Iatrogenic withdrawal syndrome (IWS) poses a significant clinical challenge in pediatric intensive care units (PICUs) within Japan. Despite the existing availability of tools to assess pain and delirium, a validated instrument specificall...

  • Review
  • Open Access
28 Citations
8,741 Views
17 Pages

Sleep and Delirium in Pediatric Critical Illness: What Is the Relationship?

  • Amy Calandriello,
  • Joanna C. Tylka and
  • Pallavi P. Patwari

10 October 2018

With growing recognition of pediatric delirium in pediatric critical illness there has also been increased investigation into improving recognition and determining potential risk factors. Disturbed sleep has been assumed to be one of the key risk fac...

  • Article
  • Open Access
2 Citations
2,592 Views
9 Pages

Association between Platelet Transfusion and Delirium in Critically Ill Children

  • Matthew Nelligan,
  • Marianne E. Nellis,
  • Elizabeth A. Mauer,
  • Linda M. Gerber and
  • Chani Traube

Delirium is a frequent, serious, and preventable complication in critically ill children. Inflammation has been implicated as a mechanism for the development of delirium. Platelet transfusions may potentiate the body’s pro-inflammatory response...

  • Review
  • Open Access
56 Citations
18,940 Views
26 Pages

23 April 2021

Critically ill pediatric patients often require complex medical procedures as well as invasive testing and monitoring which tend to be painful and anxiety-provoking, necessitating the provision of analgesia and sedation to reduce stress response. Ach...

  • Article
  • Open Access
10 Citations
3,020 Views
9 Pages

Relationship between Fasting Times and Emergence Delirium in Children Undergoing Magnetic Resonance Imaging under Sedation

  • Ayşe Neslihan Balkaya,
  • Canan Yılmaz,
  • Çağdaş Baytar,
  • Asiye Demirel,
  • Nermin Kılıçarslan,
  • Filiz Ata,
  • Nurcan Kat Kaçmaz and
  • Mehmet Gamlı

16 December 2022

Background and Objectives: This study aimed to determine whether there is a relationship between preoperative fasting time, fasting blood glucose (FBG), and postoperative emergence delirium (ED) in pediatric patients undergoing MRI under sedation. Ma...

  • Article
  • Open Access
2 Citations
2,192 Views
11 Pages

19 June 2024

Background/Objectives: Preoperative fasting guidelines traditionally aim to reduce pulmonary aspiration risk. However, concerns over the adverse effects of prolonged fasting have led to exploring alternatives. This study aimed to investigate the impa...

  • Article
  • Open Access
2 Citations
4,290 Views
11 Pages

Melatonin Use in Pediatric Intensive Care Units: A Single-Center Experience

  • Jessica L. Jacobson,
  • Joanna Tylka,
  • Savannah Glazer,
  • Yanyu Zhang,
  • Rosario Cosme,
  • Jean M. Silvestri and
  • Pallavi P. Patwari

28 August 2023

Growing evidence indicates that altered melatonin secretion during critical illness may influence the quality and quantity of sleep, delirium, and overall recovery. However, limited data exist regarding the use of melatonin in pediatric critical illn...

  • Article
  • Open Access
17 Citations
6,150 Views
14 Pages

EEG-Parameter-Guided Anesthesia for Prevention of Emergence Delirium in Children

  • Yaqian Han,
  • Mengrong Miao,
  • Pule Li,
  • Yitian Yang,
  • Hui Zhang,
  • Beibei Zhang,
  • Mingyang Sun and
  • Jiaqiang Zhang

5 September 2022

Background: Emergence delirium (ED) usually occurs in children after surgery with an incidence of 10−80%. Though ED is mostly self-limited, its potential injuries cannot be ignored. Whether electroencephalography (EEG)-parameter-guided anesthes...

  • Review
  • Open Access
1 Citations
3,284 Views
17 Pages

Sedation in Critically Ill Children

  • Stephen Playfor and
  • Lara Bunni

5 September 2025

Sedation and analgesia are crucial elements in managing discomfort and facilitating critical care interventions in children. Our choice of sedative agents has a significant impact on the physiological and psychological outcomes of our patients. Overs...

  • Review
  • Open Access
15 Citations
6,695 Views
15 Pages

The Perioperative Anesthetic Management of the Pediatric Patient with Special Needs: An Overview of Literature

  • Alessandra Ciccozzi,
  • Barbara Pizzi,
  • Alessandro Vittori,
  • Alba Piroli,
  • Gioele Marrocco,
  • Federica Della Vecchia,
  • Marco Cascella,
  • Emiliano Petrucci and
  • Franco Marinangeli

21 September 2022

The perioperative management of pediatric patients with psycho-physical disorders with related relational and cognitive problems must be carefully planned, in order to make the entire hospitalization process as comfortable and as less traumatic as po...

  • Article
  • Open Access
1 Citations
1,721 Views
10 Pages

Background/Objectives: Emergence delirium (ED) is one of the most frequent postoperative complications in pediatric patients after general anesthesia. In adults, a deeper intraoperative level of anesthesia has been reported as an independent predicto...

  • Article
  • Open Access
1,330 Views
10 Pages

11 December 2024

Background/Objectives: Postoperative delirium is a frequent complication in children undergoing general anesthesia. It has been suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium. The aim of our study was t...

  • Article
  • Open Access
6 Citations
2,485 Views
16 Pages

A Meta-Analysis of the Impact of Intranasal Dexmedetomidine on Emergence Delirium and Agitation in Children and Adolescents Undergoing Tonsillectomy and/or Adenoidectomy

  • Abbas Al Mutair,
  • Yasmine Alabbasi,
  • Bushra Alshammari,
  • Awatif M. Alrasheeday,
  • Hanan F. Alharbi and
  • Abdulsalam M. Aleid

26 February 2025

Background: Tonsillectomy and adenoidectomy are two common pediatric operations that are frequently associated with postoperative problems like emergence agitation (EA) and emergence delirium (ED). Intranasal dexmedetomidine, which has anxiolytic and...

  • Review
  • Open Access
71 Citations
12,804 Views
16 Pages

10 September 2020

The ongoing worldwide pandemic of the novel human coronavirus SARS-CoV-2 and the ensuing disease, COVID-19, has presented enormous and unprecedented challenges for all medical specialists. However, to date, children, especially neonates, have been re...

  • Article
  • Open Access
12 Citations
4,352 Views
7 Pages

The Effects of Remifentanil and Fentanyl on Emergence Agitation in Pediatric Strabismus Surgery

  • Jongyoon Baek,
  • Sang Jin Park,
  • Jun Oh Kim,
  • Minhyun Kim,
  • Do Young Kim and
  • Eun Kyung Choi

24 April 2022

Emergence agitation (EA) is one of the main concerns in the field of pediatric anesthesia using sevoflurane. We investigated the effects of remifentanil and fentanyl on the incidence of EA in pediatric patients undergoing strabismus surgery. Ninety c...

  • Review
  • Open Access
1 Citations
3,765 Views
16 Pages

28 April 2025

Background/Objectives: Efficient postoperative recovery room care in pediatric patients is crucial for optimizing perioperative safety, patient outcome, and effective pain management. However, this area is frequently underemphasized, leading to highe...

  • Case Report
  • Open Access
3,428 Views
5 Pages

20 February 2024

Controlling preoperative anxiety is necessary in pediatric patients to avoid adverse effects such as emergence delirium, behavioral problems, post-traumatic stress disorder, anxiety prior to future procedures, and increased analgesic doses in the rec...

  • Viewpoint
  • Open Access
8 Citations
3,086 Views
7 Pages

28 February 2023

Unsettled behaviors characterize the early phase after general anaesthesia in the pediatric population in up to 80% of cases. Emergence delirium (ED) and acute pain are the two most relevant sources of this phenomenon. Research and clinical guideline...

  • Article
  • Open Access
12 Citations
4,651 Views
11 Pages

The Use of Bispectral Index Monitoring Does Not Change Intraoperative Exposure to Volatile Anesthetics in Children

  • Cornelius A. Sullivan,
  • Chinyere Egbuta,
  • Raymond S. Park,
  • Karina Lukovits,
  • David Cavanaugh and
  • Keira P. Mason

30 July 2020

The exposure of infants and children to volatile anesthetics, such as sevoflurane, has been a topic of concern with respect to the potential risk for long term neurocognitive effects. The primary objective of this study was to determine whether the p...

  • Article
  • Open Access
4 Citations
2,504 Views
12 Pages

12 February 2023

Congenital heart defect (CHD) surgeries are performed with cardiopulmonary bypass (CPB) and are complicated by several factors that affect the child’s brain. However, to date, the number of studies on brain protection in cardiac surgery remains...

  • Article
  • Open Access
5 Citations
3,556 Views
8 Pages

15 August 2020

The aim of this prospective observational study was to determine if children undergoing bilateral myringotomy and tympanostomy tube insertion with a sevoflurane anesthetic plus intravenous propofol and ketorolac experienced a lower incidence of emerg...