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11 Results Found

  • Review
  • Open Access
17 Citations
5,591 Views
23 Pages

The Human Gut Virome and Its Relationship with Nontransmissible Chronic Diseases

  • Shahrzad Ezzatpour,
  • Alicia del Carmen Mondragon Portocarrero,
  • Alejandra Cardelle-Cobas,
  • Alexandre Lamas,
  • Aroa López-Santamarina,
  • José Manuel Miranda and
  • Hector C. Aguilar

15 February 2023

The human gastrointestinal tract contains large communities of microorganisms that are in constant interaction with the host, playing an essential role in the regulation of several metabolic processes. Among the gut microbial communities, the gut bac...

  • Article
  • Open Access
55 Citations
11,188 Views
15 Pages

Virome of a Feline Outbreak of Diarrhea and Vomiting Includes Bocaviruses and a Novel Chapparvovirus

  • Yanpeng Li,
  • Emilia Gordon,
  • Amanda Idle,
  • Eda Altan,
  • M. Alexis Seguin,
  • Marko Estrada,
  • Xutao Deng and
  • Eric Delwart

4 May 2020

An unexplained outbreak of feline diarrhea and vomiting, negative for common enteric viral and bacterial pathogens, was subjected to viral metagenomics and PCR. We characterized from fecal samples the genome of a novel chapparvovirus we named fechavi...

  • Article
  • Open Access
514 Views
12 Pages

6 November 2025

Psittacine bornavirus type-4 (PaBV-4) causes proventricular dilatation disease and death among diverse birds, most notably caged parrots and related species, with no known cure or vaccine. Infected birds can shed virus in fecal matter, urine, and fea...

  • Review
  • Open Access
20 Citations
5,433 Views
17 Pages

The Roles of the Virome in Cancer

  • Felix Broecker and
  • Karin Moelling

Viral infections as well as changes in the composition of the intestinal microbiota and virome have been linked to cancer. Moreover, the success of cancer immunotherapy with checkpoint inhibitors has been correlated with the intestinal microbial comp...

  • Review
  • Open Access
151 Citations
22,842 Views
36 Pages

Persistence of Pathogens on Inanimate Surfaces: A Narrative Review

  • Jan Erik Wißmann,
  • Lisa Kirchhoff,
  • Yannick Brüggemann,
  • Daniel Todt,
  • Joerg Steinmann and
  • Eike Steinmann

For the prevention of infectious diseases, knowledge about transmission routes is essential. In addition to respiratory, fecal–oral, and sexual transmission, the transfer of pathogens via surfaces plays a vital role for human pathogenic infections—es...

  • Article
  • Open Access
2 Citations
2,877 Views
18 Pages

Sexual Dimorphism Has Low Impact on the Response against Rotavirus Infection in Suckling Rats

  • Carla Morales-Ferré,
  • Ignasi Azagra-Boronat,
  • Malén Massot-Cladera,
  • Àngels Franch,
  • Margarida Castell,
  • María José Rodríguez-Lagunas and
  • Francisco J. Pérez-Cano

Rotaviruses (RVs) are the leading pathogens causing severe and acute diarrhea in children and animals. It is well known that sex contributes to shaping immune responses, thus it could also influence the incidence and severity of the RV infection. The...

  • Article
  • Open Access
1 Citations
850 Views
20 Pages

Changes in Gut Phageome and Bacteriome Following Fecal Microbiota Transfer in Patients with Intestinal Graft-Versus-Host Disease and Crohn’s Disease

  • Alexei B. Chukhlovin,
  • Oleg V. Goloshchapov,
  • Oksana B. Shchukina,
  • Aleksandra M. Kharitidis,
  • Alexander A. Zhloba,
  • Tatiana F. Subbotina,
  • Aleksey V. Kusakin,
  • Oleg V. Kosarev,
  • Viktoria V. Tsai and
  • Oleg S. Glotov
  • + 2 authors

Intestinal bacterial dysbiosis develops in a number of immune-mediated disorders. Fecal microbiota transfer (FMT) is considered a potentially efficient tool for restoration of the patient’s gut microbiota. The aim of our study was to trace the...

  • Article
  • Open Access
1,145 Views
16 Pages

The Gut Microbiota of the Greater Horseshoe Bat Confers Rapidly Corresponding Immune Cells in Mice

  • Shan Luo,
  • Xinlei Huang,
  • Siyu Chen,
  • Junyi Li,
  • Hui Wu,
  • Yuhua He,
  • Lei Zhou,
  • Boyu Liu and
  • Jiang Feng

26 February 2025

Background: Emerging infectious diseases threaten human and animal health, with most pathogens originating from wildlife. Bats are natural hosts for many infectious agents. Previous studies have demonstrated that changes in some specific genes in bat...

  • Article
  • Open Access
1,516 Views
17 Pages

Uncovering SARS-CoV-2 Molecular Epidemiology Across the Pandemic Transition: Insights into Transmission in Clinical and Environmental Samples

  • Vrushali D. Patil,
  • Rashmi Chowdhary,
  • Anvita Gupta Malhotra,
  • Jitendra Singh,
  • Debasis Biswas,
  • Rajnish Joshi and
  • Jagat Rakesh Kanwar

19 May 2025

Background: Respiratory droplets are the main way in which the COVID-19 pandemic’s causal agent, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), spreads. Angiotensin-converting enzyme 2 (ACE2) receptors, especially in lung cells,...

  • Article
  • Open Access
5 Citations
2,730 Views
16 Pages

Molecular Characterization of Feline Parvovirus from Domestic Cats in Henan Province, China from 2020 to 2022

  • Zuhua Yu,
  • Wenjie Wang,
  • Chuan Yu,
  • Lei He,
  • Ke Ding,
  • Ke Shang and
  • Songbiao Chen

30 June 2024

Carnivore protoparvovirus-1, feline parvovirus (FPV), and canine parvovirus (CPV) continue to spread in companion animals all over the world. As a result, FPV and CPV underwent host-to-host transfer in carnivorous wild-animal hosts. Here, a total of...

  • Article
  • Open Access
2 Citations
2,708 Views
20 Pages

Role of Pre-Farrow Natural Planned Exposure of Gilts in Shaping the Passive Antibody Response to Rotavirus A in Piglets

  • Deepak Kumar,
  • Amanda V. Anderson Reever,
  • Jeremy S. Pittman,
  • Nora L. Springer,
  • Kylynn Mallen,
  • Gleyder Roman-Sosa,
  • Neha Sangewar,
  • Mary C. Casey-Moore,
  • Michael D. Bowen and
  • Douglas G. Marthaler
  • + 1 author

18 December 2023

Natural planned exposure (NPE) remains one of the most common methods in swine herds to boost lactogenic immunity against rotaviruses. However, the efficacy of NPE protocols in generating lactogenic immunity has not been investigated before. A longit...