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  • Article
  • Open Access
19 Citations
3,887 Views
19 Pages

Functionalized Moringa oleifera Gum as pH-Responsive Nanogel for Doxorubicin Delivery: Synthesis, Kinetic Modelling and In Vitro Cytotoxicity Study

  • Sunita Ranote,
  • Marta Musioł,
  • Marek Kowalczuk,
  • Veena Joshi and ,
  • Ghanshyam S. Chauhan,
  • Rakesh Kumar,
  • Sandeep Chauhan and
  • Kiran Kumar
  • + 3 authors+ 0 author

3 November 2022

Environment-responsive-cum-site-specific delivery of therapeutic drugs into tumor cells is a foremost challenge for chemotherapy. In the present work, Moringa oleifera gum–based pH-responsive nanogel (MOGN) was functionalized as a doxorubicin (...

(This article belongs to the Section Polymer Applications)
  • Interesting Images
  • Open Access
9 Citations
2,578 Views
7 Pages

20 September 2023

We report a rare case of spindle cell rhabdomyosarcoma. Sarcomas generally exhibit an abnormal increased FDG uptake on 18F-FDG PET/CT imaging, while spindle cell rhabdosarcomas exhibits a significantly increased lesion uptake on 68Ga FAPI PET/CT imag...

(This article belongs to the Special Issue 18F-FDG PET/CT: Current and Future Clinical Applications)
  • Article
  • Open Access
3 Citations
2,408 Views
16 Pages

Phospholipase Cδ-4 (PLCδ4) Acts as a Nuclear Player to Influence Cyclin B Expression in the Embryonal Rhabdomyosarcoma Cell Lines RD and A204

  • Sara Salucci,
  • Alberto Bavelloni,
  • Ilaria Versari,
  • Sabrina Burattini and ,
  • Francesco Bavelloni,
  • Pietro Gobbi,
  • Alessandro Fanzani,
  • Silvia Codenotti,
  • William Blalock and
  • Irene Faenza
  • + 6 authors+ 1 author

20 September 2024

Rhabdomyosarcoma (RMS), the most common form of sarcoma typical of pediatric age, arises from the malignant transformation of the mesenchymal precursors that fail to differentiate into skeletal muscle cells. Here, we investigated whether the protein...

(This article belongs to the Section Molecular Biology)