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Article

9 Citations

3,765 Views

28 Pages

Comprehensive Characterization of Phytochemical Composition, Membrane Permeability, and Antiproliferative Activity of Juglans nigra Polyphenols

Rita Osztie,
Tamás Czeglédi,
Sarah Ross,
Bence Stipsicz,
Eszter Kalydi,
Szabolcs Béni,
Imre Boldizsár,
Eszter Riethmüller,
Szilvia E. Bősze and
Ágnes Alberti

Int. J. Mol. Sci.2024, 25(13), 6930;https://doi.org/10.3390/ijms25136930

25 June 2024

The aim of our study was the detailed polyphenol profiling of Juglans nigra and the characterization of the membrane permeability and antiproliferative properties of its main phenolics. A total of 161 compounds were tentatively identified in J. nigra...

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Article

2 Citations

2,688 Views

20 Pages

Phytochemical Investigation of Polyphenols from the Aerial Parts of Tanacetum balsamita Used in Transylvanian Ethnobotany and Parallel Artificial Membrane Permeability Assay

Ágnes Alberti,
Eszter Riethmüller,
Csenge Anna Felegyi-Tóth,
Szilvia Czigle,
Dóra Czégényi,
Rita Filep and
Nóra Papp

Plants2024, 13(12), 1652;https://doi.org/10.3390/plants13121652

14 June 2024

In this study, based on ethnobotanical data recorded in Transylvania, the polyphenolic compounds and the permeability of the aerial part’s extract of Tanacetum balsamita were investigated. Ultrahigh-performance liquid chromatography-tandem mass...

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Article

6 Citations

2,911 Views

16 Pages

Membrane Permeability and Aqueous Stability Study of Linear and Cyclic Diarylheptanoids from Corylus maxima

Csenge Anna Felegyi-Tóth,
Zsófia Tóth,
Zsófia Garádi,
Imre Boldizsár,
Andrea Nagyné Nedves,
Alexandra Simon,
Kristóf Felegyi,
Ágnes Alberti and
Eszter Riethmüller

Pharmaceutics2022, 14(6), 1250;https://doi.org/10.3390/pharmaceutics14061250

12 June 2022

Seven diarylheptanoids were isolated from Corylus maxima by flash chromatography and semipreparative high-performance liquid chromatography (HPLC) and identified by Orbitrap^® mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscop...

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Article

22 Citations

9,254 Views

21 Pages

New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels

Piera Sozio,
Lisa Marinelli,
Ivana Cacciatore,
Antonella Fontana,
Hasan Türkez,
Gianfabio Giorgioni,
Dario Ambrosini,
Francesco Barbato,
Lucia Grumetto and
Antonio Di Stefano
+ 2 authors

Molecules2013, 18(9), 10747-10767;https://doi.org/10.3390/molecules180910747

3 September 2013

Alzheimer’s disease (AD) is characterized by irreversible and progressive loss of memory and cognition and profound neuronal loss. Current therapeutic strategies for the treatment of AD have been directed to a variety of targets with the aim of rever...

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Article

8 Citations

2,951 Views

18 Pages

Stereoselective Synthesis and Antiproliferative Activities of Tetrafunctional Diterpene Steviol Derivatives

Dorottya Bai,
Zsuzsanna Schelz,
Dóra Erdős,
Anna K. Kis,
Viktória Nagy,
István Zupkó,
György T. Balogh and
Zsolt Szakonyi

Int. J. Mol. Sci.2023, 24(2), 1121;https://doi.org/10.3390/ijms24021121

6 January 2023

A new family of diterpene-type aminotriol derivatives has been synthesised from stevioside in a stereoselective manner. The key intermediate spiro-epoxide was prepared through the methyl ester of the allilyc diol derived from steviol. The oxirane rin...

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Article

1 Citations

4,770 Views

19 Pages

A Digital Analysis of an Early Medieval Cultic and Ritual Change in Hampi: The Mula Virupaksha Temple in the Hemakuta Hill Sacred Space

Candis Haak

Histories2022, 2(3), 315-333;https://doi.org/10.3390/histories2030023

30 August 2022

This paper examines a 12th-century Virupaksha temple through the reconstruction and exploration of space, movement, devotee corporeal experiences, and the use of natural landscape microtopographic features in monument design. The Mula Virupaksha Temp...

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