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Article

23 Citations

8,808 Views

18 Pages

Development of an In Vitro Airway Epithelial–Endothelial Cell Culture Model on a Flexible Porous Poly(Trimethylene Carbonate) Membrane Based on Calu-3 Airway Epithelial Cells and Lung Microvascular Endothelial Cells

Thijs Pasman,
Danielle Baptista,
Sander van Riet,
Roman K. Truckenmüller,
Pieter S. Hiemstra,
Robbert J. Rottier,
Naomi M. Hamelmann,
Jos M. J. Paulusse,
Dimitrios Stamatialis and
André A. Poot

Membranes2021, 11(3), 197;https://doi.org/10.3390/membranes11030197

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11 March 2021

Due to the continuing high impact of lung diseases on society and the emergence of new respiratory viruses, such as SARS-CoV-2, there is a great need for in vitro lung models that more accurately recapitulate the in vivo situation than current models...

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Article

11 Citations

3,808 Views

16 Pages

Systemic Sclerosis Serum Significantly Impairs the Multi-Step Lymphangiogenic Process: In Vitro Evidence

Mirko Manetti,
Eloisa Romano,
Irene Rosa,
Bianca Saveria Fioretto,
Serena Guiducci,
Silvia Bellando-Randone,
Erika Pigatto,
Franco Cozzi,
Lidia Ibba-Manneschi and
Marco Matucci-Cerinic

Int. J. Mol. Sci.2019, 20(24), 6189;https://doi.org/10.3390/ijms20246189

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7 December 2019

In systemic sclerosis (SSc), the possible involvement of lymphatic microcirculation and lymphangiogenesis has traditionally been overshadowed by the greater emphasis placed on dysfunctional blood vascular system and angiogenesis. In the present in vi...

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Article

2 Citations

2,128 Views

18 Pages

Modeling the Immune Response for Pathogenic and Nonpathogenic Orthohantavirus Infections in Human Lung Microvasculature Endothelial Cells

Evan P. Williams,
Aadrita Nandi,
Victoria Nam,
Linda J. S. Allen,
A. Alexandre Trindade,
Michele M. Kosiewicz and
Colleen B. Jonsson

Viruses2023, 15(9), 1806;https://doi.org/10.3390/v15091806

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24 August 2023

Hantaviruses, genus Orthohantavirus, family Hantaviridae, order Bunyavirales, are negative-sense, single-stranded, tri-segmented RNA viruses that persistently infect rodents, shrews, and moles. Of these, only certain virus species harbored by rodents...

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