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13 Results Found

  • Article
  • Open Access
25 Citations
10,013 Views
29 Pages

Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

  • Tek N. Lamichhane,
  • N. Dinuka Abeydeera,
  • Anne-Cécile E. Duc,
  • Philip R. Cunningham and
  • Christine S. Chow

28 January 2011

Ribosomal RNA is the catalytic portion of ribosomes, and undergoes a variety of conformational changes during translation. Structural changes in ribosomal RNA can be facilitated by the presence of modified nucleotides. Helix 31 of bacterial 16S ribos...

  • Review
  • Open Access
4 Citations
2,560 Views
54 Pages

Calorimetric (from both isothermal micro-calorimetry and DSC), chiro-optical, viscometric and rheological data on aqueous solutions of pectic acid and low-methoxyl pectin (LMP), published over decades from different laboratories, have been comparativ...

  • Article
  • Open Access
13 Citations
3,889 Views
16 Pages

27 August 2019

The triple helix (university-industry-government) is a dynamic cooperation model in the area of regional innovation. With the application of this model, the authors aim to address the mechanism of how multiple participants affect innovation efficienc...

  • Article
  • Open Access
14 Citations
4,330 Views
8 Pages

How Resources of Universities influence Industry Cooperation

  • Gyeong Min Nam,
  • Dae Geon Kim and
  • Sang Ok Choi

In Korea, cooperation between university and company is mainly encouraged by government policy as the Triple Helix’s statist model. Since 2003, the government started a variety of university financial support program, and in 2014, it reached to...

  • Article
  • Open Access
5 Citations
4,014 Views
21 Pages

Structural Analysis and Dynamic Processes of the Transmembrane Segment Inside Different Micellar Environments—Implications for the TM4 Fragment of the Bilitranslocase Protein

  • Kosma Szutkowski,
  • Emilia Sikorska,
  • Iulia Bakanovych,
  • Amrita Roy Choudhury,
  • Andrej Perdih,
  • Stefan Jurga,
  • Marjana Novič and
  • Igor Zhukov

26 August 2019

The transmembrane (TM) proteins are gateways for molecular transport across the cell membrane that are often selected as potential targets for drug design. The bilitranslocase (BTL) protein facilitates the uptake of various anions, such as bilirubin,...

  • Article
  • Open Access
43 Citations
5,604 Views
15 Pages

14 January 2021

Keratin is widely recognized as a high-quality renewable protein resource for biomedical applications. A large amount of rabbit hair waste is produced in textile industries, because it has high medullary layer content, but poor spinnability. Therefor...

  • Article
  • Open Access
4 Citations
2,708 Views
14 Pages

Nanomechanical, Structural and Antioxidant Characterization of Nixtamalized Popcorn Pericarp

  • Liliana Edith Rojas-Candelas,
  • Mayra Díaz-Ramírez,
  • Adolfo Armando Rayas-Amor,
  • Rosy Gabriela Cruz-Monterrosa,
  • Juan Vicente Méndez-Méndez,
  • Adriana Villanueva-Carvajal and
  • Alejandro de Jesús Cortés-Sánchez

4 July 2022

Expanded popcorn grain is widely consumed as a healthy snack all around the world; however, the study of the behavior of its components by processes such as nixtamalization is scarce. Therefore, the aim of this work was to characterize the nanomechan...

  • Article
  • Open Access
38 Citations
7,230 Views
16 Pages

Curcumin-Gene Expression Response in Hormone Dependent and Independent Metastatic Prostate Cancer Cells

  • Shilpa Katta,
  • Arun Srivastava,
  • Rajesh L. Thangapazham,
  • Inger L. Rosner,
  • Jennifer Cullen,
  • Hua Li and
  • Shashwat Sharad

2 October 2019

The androgen receptor is one of the key targets for prostate cancer treatment. Despite its less satisfactory effects, chemotherapy is the most common treatment option for metastatic and/or castration-resistant patients. There are constant needs for n...

  • Article
  • Open Access
6 Citations
2,781 Views
10 Pages

Scorpion venom is a mixture of bioactive peptides, among which neurotoxins and antimicrobial peptides serve especially vital functions. Scorpion venom peptides in Buthidae species have been well described, but toxic peptides from non-Buthidae species...

  • Article
  • Open Access
25 Citations
8,172 Views
17 Pages

25 April 2012

Studies related to the engineering of calcium binding sites of CGTase are limited. The calcium binding regions that are known for thermostability function were subjected to site-directed mutagenesis in this study. The starting gene-protein is a varia...

  • Article
  • Open Access
10 Citations
4,114 Views
24 Pages

Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations

  • Katarzyna Bucholc,
  • Aleksandra Skrajna,
  • Kinga Adamska,
  • Xiao-Cui Yang,
  • Krzysztof Krajewski,
  • Jarosław Poznański,
  • Michał Dadlez,
  • Zbigniew Domiński and
  • Igor Zhukov

FLICE-associated huge protein (FLASH), Yin Yang 1-Associated Protein-Related Protein (YARP) and Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT) localize to discrete nuclear structures called histone locus bodies (HLBs) where they control various...

  • Article
  • Open Access
12 Citations
3,036 Views
23 Pages

Ultrasound as Green Technology for the Valorization of Pumpkin Leaves: Intensification of Protein Recovery

  • Jelena Mijalković,
  • Nataša Šekuljica,
  • Sonja Jakovetić Tanasković,
  • Predrag Petrović,
  • Bojana Balanč,
  • Marija Korićanac,
  • Ana Conić,
  • Jelena Bakrač,
  • Verica Đorđević and
  • Zorica Knežević-Jugović
  • + 1 author

26 August 2024

The recovery of valuable nutritional compounds, like proteins, from waste streams and by-products is a key strategy for enhancing production sustainability and opening up new market potential. This research aimed to use high-intensity ultrasound as a...

  • Article
  • Open Access
11 Citations
4,544 Views
17 Pages

Structural Protein Effects Underpinning Cognitive Developmental Delay of the PURA p.Phe233del Mutation Modelled by Artificial Intelligence and the Hybrid Quantum Mechanics–Molecular Mechanics Framework

  • Juan Javier López-Rivera,
  • Luna Rodríguez-Salazar,
  • Alejandro Soto-Ospina,
  • Carlos Estrada-Serrato,
  • David Serrano,
  • Henry Mauricio Chaparro-Solano,
  • Olga Londoño,
  • Paula A. Rueda,
  • Geraldine Ardila and
  • Mauricio Arcos-Burgos
  • + 6 authors

A whole-exome capture and next-generation sequencing was applied to an 11 y/o patient with a clinical history of congenital hypotonia, generalized motor and cognitive neurodevelopmental delay, and severe cognitive deficit, and without any identifiabl...