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8 Results Found

  • Brief Report
  • Open Access
4 Citations
1,861 Views
8 Pages

6 March 2025

Background: Platelets are highly enriched in microRNAs (miRNAs), which are genomically encoded 19–25 nucleotide non-coding RNAs that target complementary mRNAs through total or near-total base pairing. MiR-223 is among the most abundant miRNAs...

  • Article
  • Open Access
137 Views
12 Pages

Overcoming Clopidogrel Resistance in Carotid Artery Stenting: Experience with Ticagrelor and Ticlopidine

  • Pavol Vigláš,
  • Jan Raupach,
  • Aleš Hejčl,
  • David Černík,
  • Pavla Bradáčová,
  • Patrik Matras and
  • Filip Cihlář

Objectives: The goal of this study is to establish the incidence of high on-treatment platelet reactivity (HTPR) to aspirin and clopidogrel in patients undergoing carotid stenting and to evaluate the efficacy of ticagrelor and ticlopidine in patients...

  • Article
  • Open Access
2 Citations
3,053 Views
16 Pages

The Effectiveness of Antiplatelet Therapy and the Factors Influencing It in Patients with Acute Coronary Syndrome before and during the COVID-19 Pandemic

  • Ovidiu-Ionut Anchidin,
  • Stefan Horia Rosianu,
  • Ancuta Nemes,
  • Mihai Aldica,
  • Dan Blendea,
  • Adrian Molnar,
  • Horatiu Moldovan and
  • Dana Pop

30 December 2022

Background and Objectives: Dual antiplatelet therapy (DAPT) is essential in the treatment of patients with acute coronary syndrome (ACS). The objective of this study was to evaluate the effectiveness of antiplatelet medication in our practice and to...

  • Article
  • Open Access
10 Citations
14,446 Views
11 Pages

Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 Variations Does Not Impact Alcohol Dependence Disorder Features

  • Antonio Drago,
  • Ioannis Liappas,
  • Carmine Petio,
  • Diego Albani,
  • Gianluigi Forloni,
  • Petros Malitas,
  • Christina Piperi,
  • Antonis Politis,
  • Elias O. Tzavellas and
  • Alessandro Serretti
  • + 7 authors

We assessed a set of biological (HDL, LDL, SGOT,SGPT, GGT, HTc, Hb and T levels) and psychometric variables (investigated through HAM-D, HAM-A, GAS, Liebowitz Social Anxiety Scale, Mark & Mathews Scale, Leyton scale, and Pilowski scale) in a sample o...

  • Article
  • Open Access
9 Citations
3,856 Views
20 Pages

2 August 2019

The last two decades have witnessed an explosive growth of e-commerce applications. Existing online recommendation systems for e-commerce applications, particularly group-buying applications, suffer from scalability and data sparsity problems when co...

  • Article
  • Open Access
5 Citations
2,597 Views
15 Pages

Impact of Platelet Reactivity in ACS Patients on Clinical Outcomes with Triple Antithrombotic Therapy

  • Julia Gruttemeier,
  • Yves Cottin,
  • Hermann Yao,
  • Emmanuel De Maistre,
  • Maud Maza,
  • Laurent Bonello,
  • Marc Laine,
  • Noemie Resseguier,
  • Marianne Zeller and
  • Franck Paganelli
  • + 1 author

8 April 2021

Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients on oral anticoagulants (OAC) remains a clinical conundrum. In fact, combining an OAC with dual antiplatelet therapy (triple antithrombotic therapy, TAT) increas...

  • Article
  • Open Access
16 Citations
3,773 Views
10 Pages

Background: The aim of this prospective, a three-year follow-up study, was to establish the role of high on-treatment platelet reactivity (HTPR) in predicting the recurrence of vascular events in patients after cerebrovascular incidents, particularly...

  • Review
  • Open Access
4 Citations
3,166 Views
15 Pages

Resistance on the Latest Oral and Intravenous P2Y12 ADP Receptor Blockers in Patients with Acute Coronary Syndromes: Fact or Myth?

  • Peter Blaško,
  • Matej Samoš,
  • Tomáš Bolek,
  • Lucia Stančiaková,
  • Ingrid Škorňová,
  • Martin Jozef Péč,
  • Jakub Jurica,
  • Ján Staško and
  • Marián Mokáň

4 December 2022

Novel P2Y12 ADP receptor blockers (ADPRB) should be preferred in dual-antiplatelet therapy in patients with acute coronary syndrome. Nevertheless, there are still patients who do not respond optimally to novel ADP receptor blocker therapy, and this n...