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Lassa Fever Virology

This special issue belongs to the section “Human Virology and Viral Diseases“.

Special Issue Information

Dear Colleagues,

The mammarenavirus Lassa virus (LASV), endemic to large areas of Western Africa, is the causative agent of Lassa fever (LF), a febrile disease associated with high morbidity and mortality. Due to its impact in global health security, LASV has been included in the WHO list of priority pathogens for countermeasures development. Research over the last decade has significantly our understanding of the epidemiology and molecular and cell biology of LASV, as well as mechanisms of LF pathogenesis. These advances in our understanding of LASV biology is facilitating the development of therapeutic and prophylactic strategies to treat and prevent LF. This Special Issue of Viruses focuses on the recent progress in LASV research, including the implications of the epidemiology and genetic diversity of LASV for LF control, basic aspects of LASV molecular and cell biology, the structure–function relationship of LASV proteins, mechanisms of LF pathogenesis, as well as vaccine development and new therapeutic approaches to prevent and treat LF.

Prof. Dr. Juan De la Torre
Guest Editor

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Keywords

  • Lassa virus
  • Lassa fever
  • vaccines
  • antivirals
  • virus-host interactions
  • hemorrhagic fever
  • epidemiology
  • evolution

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Viruses - ISSN 1999-4915