Special Issue "Viruses and Inflammation"
Deadline for manuscript submissions: closed (31 January 2019).
Interests: innate immunity; inflammasomes and cell death; infectious and inflammatory diseases; nucleic acid sensing pathways
Viruses are obligate intracellular parasites, and recognition of invading viruses by intracellular sensors induces rapid production of antiviral interferons and other proinflammatory cytokines. The immune response to virus infection also involves activation of various programmed cell death pathways in infected cells. Whereas this inflammatory and cell death responses are aimed to restrict virus replication and eliminate the infectious virus, exaggerated inflammatory response often lead to tissue damage and organ dysfunction. The cellular and molecular mechanisms mediating induction of inflammatory responses during viral infections, as well as strategies to restrain damaging inflammation, are areas of active research.
This Special Issue, on Viruses and Inflammation, focuses on multiple aspects of inflammation associated with viral infections including regulation of host defence mechanisms mediating inflammatory response, the interconnected nature of cell death and inflammation, how inflammation acts as a 'double edged sword' especially in the context of virus infections in vital organs as well as recent advances in antiviral therapeutic strategies that specifically targets dampening of hyperinflammatory response. The collection of articles in this special issue will hopefully provide valuable overview regarding the mechanisms mediating inflammatory response during viral infections that may lead to new research areas and antiviral therapies.
Dr. Thirumala-Devi Kanneganti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- antiviral response
- cell death
- tissue damage