Special Issue "Replication-Competent Reporter-Expressing Viruses"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: closed (29 February 2016).
A printed edition of this Special Issue is available here.
Interests: virology; vaccines; antivirals; influenza viruses; arenaviruses; Zika virus; innate immunity; adaptive immunity; virus–host interaction
Special Issues and Collections in MDPI journals
Special Issue in Viruses: New Advances on Zika Virus Research
Special Issue in Vaccines: Feature Papers Collection on Influenza Vaccines
With the development of reverse genetics systems, recombinant viruses expressing reporter fluorescent or bioluminescent genes represent an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of infection. Expression of reporter proteins allows for direct viral detection in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, fluorescent or bioluminescence tractable replicating-compatible viruses provide an ideal tool to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-through put screening settings. In this Special Issue, we aim to review replicating-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. Contrasting advantages, we also seek to discuss disadvantages associated with these reporter-expressing viruses. Finally, we will provide rational future perspectives and additional avenues for the development, characterization, and application of recombinant, reporter-expressing, competent viruses.
Dr. Luis Martinez-Sobrido
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- reporter genes
- recombinant viruses
- replicating-competent viruses
- in vivo imaging
- dynamics of viral infections