SARS-CoV-2 Infection and COVID-19 Disease

Dear Colleagues,

In December 2019, a previously unknown coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China. SARS-CoV-2 is the causative agent of coronavirus disease 2019 (COVID-19), a world-wide pandemic that has dramatically impacted the global human public health and socioeconomic activities across the world with a magnitude not seen since the “Spanish flu” pandemic in 1918/1919.

Global efforts to develop a vaccine have resulted in several promising COVID-19 vaccine candidates with excellent safety and efficacy profiles. Currently, three vaccines have been approved by the Food and Drug Administration (FDA) for emergency use for the treatment of SARS-CoV-2 infection.

The goal of this Topical Collection “SARS-CoV-2 Infection and COVID-19 Disease” is to cover aspects related to viral infection and pathogenesis, epidemiology and evolution, virus–host interactions, prophylactic vaccine development, therapeutic antivirals, neutralizing antibodies, innate and adaptive immune responses, reverse genetics approaches, recombinant viruses, reporter-expressing viruses, animal models of viral infection, pathogenesis and transmission, and COVID-19 disease.

We hope this Topical Collection will provide researchers with new insights on the biology of SARS-CoV-2 infection and its associated COVID-19 disease with the goal of unifying efforts to develop effective countermeasures to protect against SARS-CoV-2 infection and COVID-19 disease.

Prof. Dr. Luis Martinez-Sobrido
Dr. Marta L. DeDiego
Collection Editors

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