Post-viral Superinfection: Revising the Role of Pathogens and the Host

Dear Colleagues,

Infections with viral, bacterial or fungal pathogens are common complications of respiratory viral infections, including those caused by influenza, parainfluenza viruses, coronaviruses and RSV, to name a few. Additionally, some chronic viral infections have been known to be complicated by superinfections. It is generally accepted that the resolution of these secondary infections is impaired by the primary virus itself, via a virus-mediated inhibitory effect restricting or otherwise altering the induction of appropriate innate and/or adaptive immune responses, or even virus-induced host tissue damage. Furthermore, secondary pathogens exacerbate this distorted immune response in ways that are damaging and even detrimental to the host. This Special Issue will focus on various mechanisms utilized by either primary viruses or secondary pathogens to delay, restrict or prevent host recovery.

Dr. Victor Huber
Dr. Agnieszka Rynda-Apple
Guest Editors

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