Special Issue "Regulation and Exploitation of Microtubules by Viruses"
A special issue of Viruses (ISSN 1999-4915).
Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 9841
Interests: Herpes virus assembly; cell biology; intracellular trafficking; microtubule-based trafficking within neurons
Microtubules are dynamic cytoskeletal filaments that participate in a vast and diverse array of cellular processes including transport of cargo and organelles, maintenance of organellar morphology and function, regulation of cell shape and motility and the distribution of genetic material and organelles at cell division. It is therefore no surprise that viruses, virtuosos of cellular manipulation, have evolved strategies to control and exploit microtubule biology to serve their own transport needs and to adjust host cell functions in support of viral replication and spread. The goal of this Special Issue of Viruses is to summarize our current understanding of the molecular details and diversity of strategies used by animal and plant viruses to take control of the microtubule network. We invite primary research and review articles concerning virus/microtubule interactions with topics of interest including, but not limited to, the following:
- Use of microtubules during the entry of viruses and virus-containing organelles.
- Recruitment of molecular motors during entry, particle disassembly, and egress.
- Viral manipulation of the centrosome and use of alternate microtubule organizing centers.
- Manipulation of microtubules during the course of an infection, including stabilization or bundling.
- Role of microtubules in the establishment and function of cytoplasmic viral replication compartments.
- Microtubule-dependent changes to host cell biology, e.g., upon function and motility of intracellular organelles, cell motility and migration, and cell division and anti-viral responses.
- Manipulation of plant and insect microtubules by plant viruses.
- Viruses in the nervous system.
Dr. Duncan W. Wilson
Manuscript Submission Information
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