Bovine Influenza

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 110

Special Issue Editors

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Guest Editor
Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40506, USA
Interests: influenza virology; bovine influenza C and D; coronavirus; rotavirus; vaccine development; reverse genetics system; pathogen discovery

E-Mail Website
Guest Editor
Department of Veterinary Science, Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY 40506, USA
Interests: bovine influenza; influenza virology; rotavirus; veterinary virology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cattle had not been proposed or established as a reservoir or susceptible host for influenza viruses until the discovery of influenza D in bovines in 2014. The recent observations of human influenza C virus spillover to cattle further strengthen the idea that cattle are susceptible to influenza virus infections. In March 2024, an in-depth clinical investigation of causative agents associated with a mystery disease complex affecting dairy cows in the Texas panhandle region of United States led to the unexpected identification of a highly pathogenic avian influenza (HPAI) H5N1 virus in diseased dairy cows with a significant drop in milk production. To date, cow influenza H5N1 has been found in at least five states of the U.S., including Texas, Kansas, Michigan, New Mexico, and Idaho. The sudden emergence of the H5N1 virus in dairy cows provides convincing evidence that cattle are also a susceptible host to the influenza A virus. This new discovery also raises many important questions, such as how the bird influenza virus jumps to dairy cows with high levels of the virus detected in raw milk, and how to protect cattle herds as well as people who work for this important industry. This Special Issue will feature the most recent research and findings on influenza viruses in cattle, including epidemiology and public health, tropism, adaptation to bovines and cross-species transmission, infection biology, evolution, virus–host interactions, immune responses, and vaccine development. In addition, this SI also welcome topics on influenza viruses in other ruminating mammals, including goats, sheep, and deer.

Dr. Dan Wang
Prof. Dr. Feng Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cattle
  • influenza viruses
  • avian influenza
  • replication
  • virulence
  • transmission
  • host adaptation
  • reservoir
  • epidemiology
  • one health
  • vaccine
  • immune response

Published Papers

This special issue is now open for submission.
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