Elimination of Viral Hepatitis: Improving Diagnosis, Treatment and Surveillance 2.0

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".

Deadline for manuscript submissions: 16 August 2024 | Viewed by 1162

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Guest Editor
Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Piazza Miraglia 2, 80138 Naples, Italy
Interests: chronic HCV hepatitis; viral hepatitis; non-alcoholic fatty liver disease; metabolic syndrome; SARS-CoV-2
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Special Issue Information

Dear Colleagues,

This Special Issue of Viruses will explore key challenges in the global elimination of viral hepatitis. It will particularly focus on three broad areas of research that are all needed to reduce the global burden of viral hepatitis. First, it will report innovations in diagnostics to improve and simplify the process of obtaining a reliable, low-cost, and quick diagnosis. Second, it will explore novel pathways that link people to care and treatment, making treatment services acceptable and reducing stigma. Third, it will examine surveillance systems and interventions in healthcare data to monitor progress toward elimination. This Special Issue aims to publish cross-disciplinary submissions including epidemiology, clinical, health services, and social research focused on viral hepatitis.

Dr. Riccardo Nevola
Guest Editor

Manuscript Submission Information

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Keywords

  • viral hepatitis
  • hepatitis B
  • hepatitis C
  • elimination
  • diagnosis
  • treatment uptake
  • surveillance

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Published Papers (1 paper)

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Research

10 pages, 1522 KiB  
Article
Change in Prevalence of Hepatitis B Virus Infection in Pregnant Women in the Last Two Decades in Thailand
by Yosagorn Porngasemsart, Sirinart Sirilert and Theera Tongsong
Viruses 2024, 16(2), 314; https://doi.org/10.3390/v16020314 - 19 Feb 2024
Viewed by 953
Abstract
Objectives: In Thailand, there has been a strategy to prevent the mother-to-child transmission of HBV for over 30 years. However, there is still a lack of empirical evidence regarding the effectiveness of this strategy. This study aims to investigate the trends in the [...] Read more.
Objectives: In Thailand, there has been a strategy to prevent the mother-to-child transmission of HBV for over 30 years. However, there is still a lack of empirical evidence regarding the effectiveness of this strategy. This study aims to investigate the trends in the prevalence of HBV infection in pregnant women and to identify factors that may be associated with the prevalence of HBV infection in pregnant women. Patients and Methods: A maternal–fetal medicine database was accessed to retrieve the consecutive obstetric records of women giving birth at Chiang Mai University Hospital, Thailand, from January 2003 to December 2022. All women undergoing HBV tests with available results were included for an analysis of the trends and changes in the prevalence of maternal HBV infection. Also, the rates of infection in different age cohorts were compared. Results: During the study period, a total of 36,958 women were eligible for analysis. Overall, the prevalence of HBV infection in pregnant women was found to be 5.3% (1970 cases). Overall, HBV prevalence fell from 6.11% in 2003 to 3.15% in 2022. There was a significant reduction, especially in the adolescent group, decreasing from 8.26% in 2003 to 0% in 2022. In the reproductive age group, the prevalence significantly decreased from 6.41% to 2.01%. However, the prevalence in the elderly group was unchanged. The only significant risk factor was the years in the early timeline of the study period, presumably associated with previous HBV vaccination. Other factors, such as socioeconomic status, residential area, and being a private case, were not correlated with the prevalence of HBV. Conclusion: The prevalence of HBV infection in pregnant women has significantly decreased in the past two decades from 6.11% in 2003 to 3.15% in 2022. The percentage of reduction was very striking in the adolescent group, dropping from 8.6% in 2003 to 0.0% in 2022 or being nearly eradicated in the most recent years. Our results suggest that the overall prevalence of HBV infection among our pregnant women will probably be less than 1.0% in the near future. Full article
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