Rabies Virus: Treatment and Prevention—2nd Edition
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 3
Special Issue Editor
Interests: rabies treatment; rabies pathogenesis; Lyssavirus rabies molecular biology; virus-host coevolution
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Rabies is a 100% lethal zoonotic encephalitis caused by Lyssavirus species, chiefly, Lyssavirus rabies or rabies virus (RABV), which leads to 55,000 human deaths each year. Rabies patients experience extensive suffering, and there is no rational treatment currently available. Treatment must include the clearance of lyssavirus infection, targeting either the virus itself or host factors, the recovery of the damaged neural tissues, and physiotherapy. Attempts to treat human patients with a combination of antivirals have resulted in few survivors, and although reports have shown that antivirals can impair RABV replication both in vitro and in vivo, the field of rabies treatment lags behind compared to the progress in viral diseases, mainly due to it being a neglected area of study. Despite efforts to control rabies in reservoirs and the availability of highly effective pre- and post-exposure immunoprophylaxis, there is still a key need in this research field to develop a treatment for patients who are not protected by these preventive measures.
This Special Issue will showcase in silico, in vitro, and in vivo experiments in antivirals against lyssaviruses, as well as the results of clinical trials and innovative approaches to the prevention of rabies.
Dr. Paulo Eduardo Brandão
Guest Editor
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Keywords
- rabies
- antiviral
- treatment
- prevention
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Related Special Issue
- Rabies Virus: Treatment and Prevention in Viruses (5 articles)
