Respiratory Viral Pathogenesis and Host-Microbe Crosstalk: From Bench to Bedside

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".

Deadline for manuscript submissions: 1 December 2026 | Viewed by 6

Special Issue Editors


E-Mail Website
Guest Editor
Department of Microbiology, The Institute of Clinical Virology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China
Interests: respiratory syncytial virus; pathogenesis; host-microbe crosstalk; viral RNA detection; prevention and treatment

E-Mail Website
Guest Editor
Division of Respiratory Medicine, SickKids, University of Toronto, Toronto, ON, Canada
Interests: respiratory epithelial cell biology; pediatric lung disease; respiratory viral infections; respiratory syncytial virus; asthma; cystic fibrosis; in vitro models; vaping

Special Issue Information

Dear Colleagues,

Respiratory viruses pose a significant global health threat, with clinical outcomes ranging from mild symptoms to severe pneumonia. Their clinical variability is driven by interactions among viruses, host immunity, and the respiratory microbiota. This special issue highlights recent advances in respiratory viral infections, focusing on the following key topics:

  • Epidemiology and Transmission:Exploring the transmission dynamics of SARS-CoV-2, influenza, and RSV, etc., with a focus on how virus–host interactions shape their spread.
  • Molecular and Cellular Biology:Insights into viral entry, replication, host–virus interactions, pathogenesis mechanisms, and mechanisms of immune evasion and cellular damage.
  • Immunology:Characterizing innate and adaptive immune responses, inflammatory regulation, and immunopathology such as cytokine storms.
  • Microbiota-Virus Interactions:Exploring how respiratory microbiota modulate immunity and influence disease severity in bacterial-viral co-infections.
  • Clinical Research:Translating fundamental discoveries into clinical applications through biomarkers, etiological diagnostics, and therapies, as well as disease management and the monitoring of progression.
  • Therapeutics and Vaccines:Advances in antivirals, immunotherapies, and vaccines to enhance prevention and the treatment of respiratory viruses.
  • Public Health and Policy:Developing evidence-based policies for epidemic preparedness, infection control, and improved respiratory disease management.

Prof. Dr. Shenghai Huang
Dr. Theo J. Moraes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • respiratory viruses
  • pathogenesis
  • host–microbe crosstalk
  • etiological diagnosis
  • prevention and treatment
  • RSV
  • influenza
  • coronavirus

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Published Papers

This special issue is now open for submission.
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