Advances in HSV
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 1280
Special Issue Editors
Interests: herpes simplex virus-1; herpes stromal keratitis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Herpes Simplex virus (HSV) infections are quite common in humans. There are two types of HSV: HSV-1 and HSV-2. According to the World Health Organization (WHO), approximately 3.8 billion people worldwide under the age of 50 are infected with HSV-1, while an estimated 520 million people worldwide aged 15–49 have contracted HSV-2. HSV is a neurovirulent virus. After infection, HSV-1 and HSV-2 are transported through axons to the neuronal soma in the sensory ganglia, where they can establish lifelong latency. The virus can become reactivated and travel via anterograde axonal transport to peripheral sites, where it can cause the development of painful lesions. HSV-1 is widely known to cause oral lesions, whereas HSV-2 generally spreads via sexual contact and causes genital herpes. In addition to oral infection, HSV-1 can cause ocular herpes, also known as herpes simplex keratitis, a condition that is quite prevalent worldwide. Herpes stromal keratitis (HSK), a type of herpes simplex keratitis, is a major cause of vision loss due to eye infections. Both viruses can also cause neurological complications, with HSV-2 being the primary cause of neonatal herpes encephalitis. Our aim in launching this Special Issue, “Advances in HSV”, is to publish review and research articles on HSV-1 and HSV-2 infections.
Dr. Susmit Suvas
Prof. Dr. James Chodosh
Guest Editors
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Keywords
- HSV-1
- HSV-2
- latency
- herpes epithelial keratitis
- herpes stromal keratitis
- HSV vaccine
- herpes simplex encephalitis
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