Current Research in Bovine Uterine Infection

A special issue of Veterinary Sciences (ISSN 2306-7381).

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 2504

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Guest Editor
College of Veterinary Medicine, Yangzhou University, Yangzhou 225012, China
Interests: bovine endometritis
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Dear Colleagues,

After parturition, the bovine uterine lumen becomes contaminated, and persistence of pathogenic microorganism often leads to uterine infection, such as metritis and endometritis. The consequence of the disease could be subfertility and even infertility, and eventually huge financial losses. Risk factors involve the species and load of bacteria, metabolic disorders, unhygienic conditions, endocrine disturbances, and concomitant reproductive abnormalities. However, most of these factors are not particularly amenable to intervening to reduce the disease. Research advances in bovine uterine infection could shed light on new strategies for the prevention and treatment of the disease. This Special Issue on “Current Research in Bovine Uterine Infection” invites reviews and original articles to update knowledge and present the most recent scientific data regarding bovine uterine infection. It is hoped that this issue will stimulate collaboration between scientists engaged in all aspects of this field of research.

Dr. Luying Cui
Guest Editor

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Keywords

  • endometritis
  • uterine infection
  • uterine health
  • animal reproduction

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Published Papers (1 paper)

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Research

18 pages, 1308 KiB  
Article
Investigating Polymorphisms and Expression Profile of Immune, Antioxidant, and Erythritol-Related Genes for Limiting Postparturient Endometritis in Holstein Cattle
by Mona Al-Sharif, Mohamed Abdo, Omnia El Shabrawy, Eman M. Abu El-Naga, Liana Fericean, Ioan Banatean-Dunea and Ahmed Ateya
Vet. Sci. 2023, 10(6), 370; https://doi.org/10.3390/vetsci10060370 - 23 May 2023
Cited by 8 | Viewed by 1867
Abstract
This study looked at genetic polymorphisms and transcript levels of immune, antioxidant, and erythritol-related markers for postparturient endometritis prediction and tracking in Holstein dairy cows. One hundred and thirty female dairy cows (65 endometritis affected and 65 apparently healthy) were used. Nucleotide sequence [...] Read more.
This study looked at genetic polymorphisms and transcript levels of immune, antioxidant, and erythritol-related markers for postparturient endometritis prediction and tracking in Holstein dairy cows. One hundred and thirty female dairy cows (65 endometritis affected and 65 apparently healthy) were used. Nucleotide sequence variations between healthy and endometritis-affected cows were revealed using PCR-DNA sequencing for immune (TLR4, TLR7, TNF-α, IL10, NCF4, and LITAF), antioxidant (ATOX1, GST, and OXSR1), and erythritol-related (TKT, RPIA, and AMPD1) genes. Chi-square investigation exposed a noteworthy variance amongst cow groups with and without endometritis in likelihood of dispersal of all distinguished nucleotide variants (p < 0.05). The IL10, ATOX1, and GST genes were expressed at substantially lower levels in endometritis-affected cows. Gene expression levels were considerably higher in endometritis-affected cows than in resistant ones for the genes TLR4, TLR7, TNF-α, NCF4, LITAF, OXSR1, TKT, RPIA, and AMPD1. The sort of marker and vulnerability or resistance to endometritis had a significant impact on the transcript levels of the studied indicators. The outcomes might confirm the importance of nucleotide variants along with gene expression patterns as markers of postparturient endometritis susceptibility/resistance and provide a workable control plan for Holstein dairy cows. Full article
(This article belongs to the Special Issue Current Research in Bovine Uterine Infection)
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