Genetic Biomarkers, Molecular Markers and Pathogenesis of Livestock Disease

Dear Colleagues,

Along with our understanding of diseases, the incidence of hereditary diseases in livestock has been increasing year by year. In 1980, there were 346 known hereditary diseases (110 in cattle, 148 in pigs and 88 in sheep). There are more than 400 kinds of diseases, such as: bovine umbilical hernia, penis and foreskin defects, hydrocephalus, tendon contracture, inguinal hernia, cryptorchidism, umbilical hernia, anal and rectal atresia in pigs, etc. In hereditary diseases, they belong to the gene or chromosome disease. However, we know very little about the scientific reasons behind the phenotypes. To promote the diagnosis, treatment and prevention of animal genetic disease, it is indispensable for scientists to identify new molecular markers and seek the real mechanisms of the incidence of disease.

In this Special Issue, we welcome summaries on the up-to-date findings about novel genetic biomarkers, molecular mechanisms or new technology, focusing on livestock disease. Moreover, we want to define novel genetic or molecular mechanisms of animal disease. We will highlight searching for the relevant and novel targets or drugs and apply them to animal breeding and reduce the burden of animal disease. The above research will lead to new and exciting future studies.

We welcome contributions in various forms (original research, reviews, mini-reviews, methods, perspective articles, etc.) highlighting, but not limited to, the following subjects:

1. Updating the knowledge about the regulatory mechanism of animal breeding in multiple stress responses.
2. Elucidating the novel endocrine regulatory mechanism of animal pathological physiology.
3. Seeking the molecular mechanisms of animal genetic disease.
4. Identifying new molecular markers linking animal economic traits (via various omics methods: proteomics, genomics, transcriptomics, metabolomics, multiple omics analysis, etc.).
5. Making innovative and challenging hypotheses aimed at reducing the burden of animal breeding or disease, based on the existing scientific evidence.

Prof. Dr. Yafei Cai
Guest Editor

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