Journal Menu► ▼ Journal Menu
Journal Browser► ▼ Journal Browser
Special Issue "Plant Toxins and Related Proteins: Pharmacology and Toxicology"
Deadline for manuscript submissions: 31 March 2020.
Interests: Lectins structure and function, Toxicology of lectins and ribosome-inactivating protein (RIPs), Toxicology of RNasas from plants, Interactions of lectins with food and intestinal mucosa, Hematology and parasitology
For a long time, we have been interested in improving our knowledge about how plants can defend themselves against viruses, bacteria, fungi, nematodes, and other hazards like environmental changes that surround them. There are several reports in the literature describing plant proteins involved in defense mechanisms, such as lectins, ribosome-inactivating proteins (RIPs), inhibitors of proteolytic enzymes, and glycohydrolases, which have been supposedly developed as an evolutionary mechanism for self-protection. These proteins are substances produced as secondary metabolites, and since their action mechanisms are based on their chemical components, some of them share structural and functional properties.
Natural toxins are present in a wide variety of plants. Some of these plants are commonly consumed as food; therefore, eaten in a certain amount, they can be harmful to human or animal health and lead to disease. The toxicological effects following ingestion of plant toxins may range from acute small alterations (gastroenteritis, arrhythmias, etc.) to severe problems and death. Plant toxins act by altering specific mechanisms involving enzymes, receptors, and even genetic material in particular cells and tissues. Nevertheless, many aspects of their toxicity are still unknown and require particular attention, since their accidental consumption or use as biological weapons are possible. Furthermore, some plant protein toxins and plant toxin-related proteins have been used in targeted experimental therapy, especially for cancer treatment.
Focusing on plant toxins and related proteins, this Special Issue aims to highlight these substances, describe their characteristics and physiological and pathological effects, as well as their applicability in nutrition and medicine. Accordingly, articles that deal with these issues are welcome.
Prof. Dr. Maria Angeles Rojo
Prof. Dr. Manuel Garrosa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Plant toxins,
- Recombinant plant toxins,
- Toxicity in vitro and in vivo