Special Issue "Insecticidal Toxins"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 January 2012).
Interests: pore-forming toxins; biological control; cellular and molecular mode of action of insecticidal bacterial and plant toxins
Interests: population genetics; environmental biology; host-parasite coevolutionary processes; diptera resistance to bioinsecticides
Interests: toxic proteins and peptides; including insecticidal and antifungal proteins; lectins; proteinases and proteinase inhibitors; phospholipases; neurotoxins; toxins affecting blood coagulation; platelets; pro-inflammatory cells
Agricultural and forestry crops continue to be significantly afflicted by insect pests, and insects, as disease vectors, remain a considerable threat to human and animal health worldwide. Furthermore, the landscape of pest control is shifting, with increasing concerns about sustainability of natural resources, climate change and pests and disease redistribution on the planet. Most pest control strategies rely on the use of chemical pesticides, with the inevitable onset of resistance and detrimental effects on biodiversity, on the environment and on public health. Biological alternatives ranging from classical biocontrol to the use of biological insecticides have been available for many years, but despite their well documented advantages over chemicals in terms of resistance development and respect of health and the environment, they still represent only a small fraction of the overall pest control effort, because of higher cost, higher labour intensiveness, lesser immediate efficiency and a rather slowly developing public awareness and demand. This special issue on Insecticidal Toxins intends to provide an overview on current progress made in the research and development of biologically based insecticides derived from bacteria, fungi, plants and arthropods. The biological aspects and issues will be addressed at the molecular, the cellular and the population levels. More specifically, it is expected that this issue of Toxins will constitute an update on topics like host biology, mode of action of insecticidal toxins, synergisms, cell responses to toxin aggression, host resistance, interguild interactions, environmental persistence, effects on non-target organisms, transgenic constructs, impact on human health, etc. Furthermore, the use of biological toxins as templates for synthetic insecticides will also be considered. Finally, the economic and social impact of the use of insecticidal toxins will be covered, e.g. public good vs. commercial approaches, regulatory policies, risk assessment, evaluation and communication, and users’ and public attitudes.
Prof. Dr. Jean-Louis Schwartz
Prof. Dr. Laurence Després
Prof. Dr. Célia Carlini
- bacterial toxin
- biological control
- disease vector
- genetically modified organism
- insect pest
- microbial pesticide
- mode of action
- plant toxin
- public health
- public perception
- transgenic organism
- transgenic plant