Special Issue "Preparation of Bacterial Cellulose and its Biomedical Applications"
Deadline for manuscript submissions: 31 May 2020.
b. Institute for Automation , Faculty of Electrical Engineering and Computer Science, University of Maribor, Smetanova ulica, 17 SI-2000 Maribor, Slovenia
Interests: Biochemical modifications (cross-linking, grafting, fluorescent labelling) of (bio)polymers: gelatin and nanocellulose (CNF, CNC, bacterial); (Bio)polymers processing into 3D composite structures (membranes, scaffolds, porous monoliths) by freeze-drying, freeze-thawing, solvent casting, and combination their off for medical and technical ap; Physic-chemical assessment, microstructure.
Bacterial cellulose (BC) is one of the most established biopolymers in the field of biomedical materials research. It is an exopolysaccharide and firmly structured at the air–liquid interphase when produced by gram-negative aerobic bacteria species, mainly Komagataeibacter xylinus. As randomly assembled nonwoven from ribbon-like fibrils composed of elementary nanofibrils, it delivers a combination of exclusive properties, such as biomimetic, collagen-like structure with high flexibility and water holding capacity, crystallinity, mouldability, compounding capacity, and lignin and hemicellulose-free chemistry. These characteristics contribute to its inherent biocompatibility, thus, attracting wide research interest in regeneration medicine, in areas such as development of artificial skin, wound dressing, blood vessels, nerve surgery, dura mater prosthesis, hemostatic material, electronic platforms, implants for cartilage and bone repair, etc. Commercial BC-based products, currently on the market, are evidence for its inherent relevance in areas such as burn and wound care, as well as periodontal treatment.
The propensity of hydroxyl surface groups opens a variety of pathways toward the surface functionalization of BC. Periodate oxidation offers partial control over BC’s degradability, even evoking physiological resorption. On the other hand, the intrinsic nanofibrilar structure allows accommodation/embedding of bioactive agents of interest. The composites containing neat or in situ or ex situ modified BC even outperforms the single (membrane) material, advancing the bionic design and leading to further progress in regenerative medicine and tissue engineering
Even comprehensively described, BC processing and applications in biomedical filed present an inexhaustible source of research ideas, encouraging many research teams to work on it.
To this end, we invite you to submit original research articles and review articles, covering the following topics:
- BC production and cost-effective carbon sources
- BC-based particles, membranes, and 3D matrices
- Amino acid and protein-supplemented BC membranes
- BC/polymer-based composites
- BC in regenerative medicine
- BC in organoids development
- BC toxicity and safety
We look forward to your submissions of new and perspective studies involving BC.
Dr. Selestina Gorgieva
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