Special Issue "Structurally and/or Biologically Novel Natural Products from Medicinal Plants"

A special issue of Plants (ISSN 2223-7747).

Deadline for manuscript submissions: 20 August 2020.

Special Issue Editor

Dr. Ki Hyun Kim
Website
Guest Editor
Natural Product Research Laboratory, School of Pharmacy, Sungkyunkwan University, 2066, Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea
Interests: natural product chemistry; isolation; HPLC purification; structural elucidation using NMR data; medicinal plant; mushroom metabolites

Special Issue Information

Dear Colleagues,

Medicinal plants have been used for a long time for the treatment and prevention of various human diseases as traditional medicines and folk medicines worldwide. Thus, medicinal plants have been recognized as an important source of novel biologically active secondary metabolites, including phenolics, flavonoids, stilbenes, tannins, terpenoids, and alkaloids. Up to now, drug discovery from medicinal plants has led to the isolation of valuable molecules such as cocaine, codeine, digitoxin, and quinine, in addition to morphine, some of which are still in use. Medicinal plants continue to provide new and important leads against various pharmacological targets, including cancer, HIV/AIDS, Alzheimer's, malaria, and pain, and, recently, plant-derived natural products have been introduced to the United States market, including arteether, galantamine, nitisinone, and tiotropium, or are currently involved in late-phase clinical trials. For these reasons, interest in medicinal plants and in their active compounds is currently increasing.

This Special Issue aims to integrate original research or review articles regarding studies of natural products chemistry from medicinal plants, including the extraction, isolation, and structural elucidation of structurally and/or biologically novel natural products as well as the evaluation of the biological properties of specific isolated compounds and their molecular targets and pharmacological activity.

Dr. Ki Hyun Kim
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medicinal plants
  • isolation
  • structural elucidation
  • new compounds
  • biologically active compounds
  • biological activity
  • molecular mechanisms

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Open AccessArticle
Biocompatibility and Antimicrobial Activity of Reynoutria elliptica Extract for Dental Application
Plants 2020, 9(6), 670; https://doi.org/10.3390/plants9060670 - 26 May 2020
Abstract
This study was conducted to determine whether nature-derived Reynoutria elliptica extracts exhibit biocompatibility and antimicrobial effects against oral pathogens such as Streptococcus mutans and Candida albicans. Fine particles of Reynoutria elliptica extract were used to probe for biocompatibility and antimicrobial activity toward [...] Read more.
This study was conducted to determine whether nature-derived Reynoutria elliptica extracts exhibit biocompatibility and antimicrobial effects against oral pathogens such as Streptococcus mutans and Candida albicans. Fine particles of Reynoutria elliptica extract were used to probe for biocompatibility and antimicrobial activity toward these pathogens, and results were evaluated with an MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay, spectrophotometric growth inhibitory assay, the total number of colony-forming units (CFU), an agar disk diffusion test, and scanning electron microscopy (SEM). In addition, UV/VIS spectroscopy was used to determine the levels of flavonoid and polyphenol in experimental solutions. Several experimental groups showed cell viability higher than 70%, and the antimicrobial activity toward both S. mutans and C. albicans was significantly higher than was that seen for the control group. In CFU and agar disk diffusion tests with C. albicans, increases in the concentration of Reynoutria elliptica extract led to significantly increased antimicrobial effects. Additionally, SEM results showed that Reynoutria elliptica extract changed the morphology and density of S. mutans and C. albicans. The results of this research can be applied to the use of Reynoutria elliptica extracts for the development of oral products that are biologically friendly and can control oral diseases such as dental caries and candida-associated denture stomatitis. Full article
Show Figures

Figure 1

Back to TopTop