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Bioactive Phytochemicals in Plants: Structure, Function, and Biological Activity
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Bioactive Phytochemicals in Plants: Structure, Function, and Biological Activity

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 724

Special Issue Editors

Dr. K.J. Senthil Kumar

E-Mail Website
Guest Editor
Center for General Education, National Chung Hsing University, Taichung-402, Taiwan
Interests: phytomedicine, natural products, essential oils, prebiotics
Special Issues, Collections and Topics in MDPI journals
Dr. Rathinasamy Baskaran

E-Mail Website
Guest Editor
Department of Bioinformatics and Medical Engineering, Asia University, Taichung City, Taiwan
Interests: bioactive compounds; antioxidants; apoptosis; cancer; biomedicines; polyphenols
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plants have long been recognized as rich sources of bioactive compounds, with profound implications for human health and disease prevention. This Special Issue explores the intricate world of bioactive phytochemicals found in plants, delving into their structural diversity, functional significance, and biological activities. Through interdisciplinary research and cutting-edge methodologies, contributors to this Special Issue will unravel the complex mechanisms underlying the bioactivity of phytochemicals. From elucidating their molecular structures to deciphering their physiological roles, this Special Issue aims to provide comprehensive insights into the diverse functions and health-promoting properties of these natural compounds.

Topics of interest include, but are not limited to, the identification and characterization of novel phytochemicals, elucidation of their modes of action, exploration of their potential therapeutic applications, and understanding of their interactions with biological systems. By fostering a deeper understanding of bioactive phytochemicals, this Special Issue seeks to inspire further research and innovation in the field, ultimately contributing to the advancement of plant-based medicine and the promotion of human health and well-being.

Dr. K.J. Senthil Kumar
Dr. Rathinasamy Baskaran
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive phytochemicals
  • plant secondary metabolites
  • natural products
  • phytochemistry
  • phytomedicine
  • metabolomics

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Published Papers (1 paper)

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Research

14 pages, 657 KiB  
Article
Chemical Constituents and Antifungal Properties of Piper ceanothifolium Kunth Against Phytopathogens Associated with Cocoa Crops
by Yudy S. Mahecha-Jimenez, Oscar J. Patiño-Ladino and Juliet A. Prieto-Rodríguez
Plants 2025, 14(6), 934; https://doi.org/10.3390/plants14060934 - 16 Mar 2025
Viewed by 378
Abstract
In this study, the antifungal potential of chemical constituents of Piper ceanothifolium Kunth was determined against three phytopathogenic fungi associated with the cocoa crop. The methodology included the phytochemical study of the inflorescences of P. ceanothifolium, the synthesis of a chroman-4-one type [...] Read more.
In this study, the antifungal potential of chemical constituents of Piper ceanothifolium Kunth was determined against three phytopathogenic fungi associated with the cocoa crop. The methodology included the phytochemical study of the inflorescences of P. ceanothifolium, the synthesis of a chroman-4-one type derivative and the evaluation of the antifungal activity against Moniliophthora roreri, Fusarium solani, and Lasiodiplodia theobromae. The phytochemical study led to the isolation and identification of two new hydroquinones (1 and 5), together with three known compounds (hydroquinones 2 and 3, and chromene 4). The synthesis of a new chromone 6 obtained from 2 through an oxa-Michael type intramolecular cyclization is also reported. All compounds showed strong antifungal activity, with 6 (IC50 of 16.9 µM) standing out for its action against F. solani, while prenylated hydroquinones 1 (30.4 µM) and 2 (60.0 µM) were the most active against M. roreri and L. theobromae, respectively. The results of this research represent the first report of the chemical composition and antifungal properties for P. ceanotifolium, suggesting its potential use as a control method against M. roreri, F. solani, and L. theobromae. Full article
(This article belongs to the Special Issue Bioactive Phytochemicals in Plants: Structure, Function, and Biological Activity)
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