Natural Pharmaceuticals Focused on Anti-inflammatory Activities

Dear Colleagues,

Plant and fungi kingdoms synthesize and store various bioactive compounds which are related to numerous health benefits in humans and animals. Additionally, many products from natural sources show significant anti-inflammatory effects. Since inflammation plays an important role in the development and progression of different illnesses, such as arthritis, asthma, cancer, cardiovascular, neurodegenerative, and autoimmune diseases, natural products possessing anti-inflammatory properties have attracted considerable scientific attention.

This Special Issue aims to present review papers and original articles focusing on current knowledge of bioactive natural products with anti-inflammatory properties. The results of anti-inflammatory activity studies documented in vitro and in vivo are appreciated. As for many natural products, there is a lack of data related to their bioactive compounds, and special emphasis is given to the submission of articles with biomolecular experiments. The identification and quantification of compounds with anti-inflammatory properties, their physicochemical characterization, mechanisms of biological activity, and relationships between structure and bioactivity (molecular docking) are welcome as well. Studies related to the complexes of natural products and carriers (as a system for controlled release) or natural products in the final formulation are also appreciated.

Research areas may include but are not limited to:

• in vitro and in vivo study of anti-inflammatory activity of natural products
• identification and quantification of compounds with anti-inflammatory properties and their physicochemical characterization
• mechanisms of anti-inflammatory activity and structure-effect relationships
• pharmaceutical formulations based on natural products with anti-inflammatory properties
• delivery and controlled-release systems for natural products with anti-inflammatory properties
• pharmaceutical process, engineering, biotechnology, and nanotechnology related to the production of natural anti-inflammatory agents
• natural anti-inflammatory agent design and targeting
• pharmacodynamics, pharmacokinetics (absorption, distribution, metabolism, and excretion), and toxicokinetics
• physiological and biochemical effects of natural anti-inflammatory agents on the body

We look forward to receiving your contributions.

Dr. Katarina Šavikin
Dr. Aleksandra A. Jovanović
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• anti-inflammatory properties
• chemical identification of natural anti-inflammatory agents
• delivery and controlled-release systems
• natural extracts
• mechanisms of natural anti-inflammatory agents
• molecular docking
• natural products
• plants and fungi
• structure–effect relationships