Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biochemical and Molecular Perspectives on Engineered Nanoparticles for Cancer Therapy submission deadline 10 Feb 2026 | Viewed by 163 | Submission Open
Keywords: cancer; oxidative stress; engineered nanoparticles (ENPs); drug delivery; biochemical processes; ferroptosis; apoptosis; cell death; molecular interactions; tumor microenvironment
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Multifunctional Natural Polymer-Based Therapeutic Systems: Drug Delivery Meets Tissue Engineering submission deadline 10 Feb 2026 | Viewed by 162 | Submission Open
Keywords: natural polymers; multifunctional biomaterials; drug delivery systems; tissue engineering; hydrogels; polymeric scaffolds; three-dimensional bioprinting; controlled release; biomimetic polymeric biomaterials; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Exploring Drug Design and Delivery Systems: Bridging Pharmacology and Biological Function submission deadline 15 Feb 2026 | Viewed by 225 | Submission Open
Keywords: drug design; drug delivery systems; pharmacology; biological function; nanotechnology; biomaterials; personalized therapeutics
(This special issue belongs to the Section Drug Targeting and Design)
Stability of Medicines and Novel Approaches for Predicting Drug Stability submission deadline 20 Feb 2026 | 12 articles | Viewed by 57797 | Submission Open
Keywords: stability; 3D printing; ICH; physical stability; biologicals
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in the Development, Characterization, and Stability Aspects of RNA-Based Vaccines
edited by and
submission deadline 20 Feb 2026 | 2 articles | Viewed by 8069 | Submission Open
Keywords: RNA-based vaccines; lyophilization; stability; gene therapy; formulation strategies; novel characterization; delivery systems; biopharmaceuticals; continuous manufacturing; AI/ML/digital twin
(This special issue belongs to the Section Gene and Cell Therapy)
Advances in Hot Melt Extrusion Technology submission deadline 20 Feb 2026 | 6 articles | Viewed by 7535 | Submission Open
Keywords: hot melt extrusion; solubility enhancement; amorphous solid dispersion; additive manufacturing; twin screw granulation; continuous manufacturing; lipid-based drug delivery systems; patient-centric dosage forms; fused deposition modeling 3D printing; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advances in Delivery of Peptides and Proteins
edited by and
submission deadline 20 Feb 2026 | 5 articles | Viewed by 5446 | Submission Open
Keywords: peptide delivery; protein delivery; bioavailability; stability; nanoparticles; encapsulation; controlled release; pharmaceutical innovation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Functionalized Polymers for Anticancer Applications
edited by Alejandro Ramirez-Jimenez, and Alexei Fedorovish Licea-Navarro
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1757 | Submission Open
Keywords: photodynamic therapy; photothermal therapy; sonodynamic therapy; immunotherapy; smart polymeric nanocarriers; specific drug delivery; functionalized polymers; anticancer drug delivery; metallodrugs; theragnostic
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Extracellular Vesicle for Drug Delivery
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1219 | Submission Open
Keywords: estracellular vesicle; exosomes; drug delivery; behavior; uptake; quantification; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative 3D Printing Techniques for Personalized Anti-Cancer Therapy
edited by Kejing Shi and
submission deadline 20 Feb 2026 | Viewed by 313 | Submission Open
Keywords: 3D printing; personalized medicine; anti-cancer therapy; bioprinting; tumor treatment; additive manufacturing; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Delivery Carriers for Anticancer Therapy
edited by
submission deadline 20 Feb 2026 | Viewed by 133 | Submission Open
Keywords: drug delivery systems; cancer therapy; nanoparticles; tumor targeting; controlled release; theranostics; liposomes; protein nanocarriers; polymeric micelles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Understanding Drug Disposition: The Interplay of Absorption, Distribution, and Excretion Processes, and Transport Mechanisms
edited by , and Carolina Inés Ghanem
submission deadline 20 Feb 2026 | Viewed by 113 | Submission Open
Keywords: transporters; drug disposition; absorption; drug interactions; drug therapy; pharmacokinetics; bioavailability; multidrug resistance
(This special issue belongs to the Section Biopharmaceutics)
Multifunctional Drug Delivery Systems
edited by
submission deadline 20 Feb 2026 | Viewed by 88 | Submission Open
Keywords: multifunctional delivery systems; nanoparticles; targeting delivery; immune-modulating delivery systems; nanoparticle conjugation; sustained drug release; smart polymers; polysaccharide-based carriers; smart nanocarrier systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Where Are We Now and Where Is Cell Therapy Headed? (2nd Edition) submission deadline 20 Feb 2026 | Viewed by 62 | Submission Open
Keywords: stem cells; mesenchymal stromal cells; cell therapy; CAR-T; CAR-NK; cancer; gene therapy; organoids and organ on a chip; extracellular vesicles; secretome
(This special issue belongs to the Section Gene and Cell Therapy)
Emerging Approaches in Neuro and Neuropsychiatric Therapeutics: Innovative Drug Discovery and Drug Delivery Strategies
edited by Alan Talevi and
submission deadline 20 Feb 2026 | Viewed by 43 | Submission Open
Keywords: central nervous system; brain; therapeutics; drug delivery; drug discovery; drug design; targeted delivery; brain delivery
(This special issue belongs to the Section Clinical Pharmaceutics)
A Commemorative Issue in Honor of Professor Gregory Gregoriadis: Liposomes for the Delivery of Drugs and Vaccines submission deadline 28 Feb 2026 | 7 articles | Viewed by 28249 | Submission Open
Keywords: liposomes for drug delivery (for therapy of cancer; infectious diseases; neurodegenerative diseases; etc.); development; applications; and challenges of ligand-targeted liposomal drugs; liposomes and biological barriers; liposomes as immunological adjuvants; cationic liposomes and lipid nanoparticles as vaccine carriers; immunization with nucleic acids in liposomes; entrapment of nucleic acid vaccines in cationic liposomes
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Population Pharmacokinetics and Its Clinical Applications
edited by and Branislava Miljković
submission deadline 28 Feb 2026 | 14 articles | Viewed by 25829 | Submission Open
Keywords: model-informed precision dosing (MIPD); therapeutic drug monitoring (TDM); dosing adjustments; special populations; nonlinear mixed-effects modeling (NONMEM); PK/PD models
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Customized Pharmaceutics: Innovations for Diverse Populations submission deadline 28 Feb 2026 | 4 articles | Viewed by 9895 | Submission Open
Keywords: nanotechnology; 3D printing; quality by design; patient-centric approaches; customized pharmaceuticals; pediatrics; geriatrics; veterinary medicine; age-appropriate formulations; taste masking
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in the Preparation and Technology of Pharmaceutical Solid Dosage Forms
edited by and Daniele Musumeci
submission deadline 28 Feb 2026 | 6 articles | Viewed by 8314 | Submission Open
Keywords: pharmaceutics; solid dosage forms; amorphous systems; crystalline systems; drug delivery systems; solid-state characterization; pharmaceutical technology; manufacturing processes
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Solid Dispersions for Drug Delivery: Development, Preparation and In Vitro/In Vivo Characterization submission deadline 28 Feb 2026 | 2 articles | Viewed by 7942 | Submission Open
Keywords: solid dispersion; poorly soluble drugs; stability; dissolution properties; molecular interaction; polymers
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Pharmaceutical Solid Dosage Forms: Manufacturing, Design, Development, and Biomedical Applications
edited by
submission deadline 28 Feb 2026 | 7 articles | Viewed by 7139 | Submission Open
Keywords: pharmaceutical solid dosage forms; pharmaceutical manufacturing; hot-melt extrusion; formulation development; 3D printing; film coating; biomaterials; polymers; drug delivery systems
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Nanomaterials and Drug Delivery Systems for Wound Healing and Antimicrobial Therapy
edited by and Marthe Carine D. Fotsing
submission deadline 28 Feb 2026 | 5 articles | Viewed by 4803 | Submission Open
Keywords: nanotherapeutics; wound dressings; nanoparticles; nanometals; antimicrobial drugs; debridement; skin regeneration; controlled delivery systems; targeted delivery systems; bioactive 3D scaffolds; scar; nanotechnology; drug delivery; chronic wounds; acute wounds; microbial infections; HIV; viral infections; fungal infections; bacterial infections; drug resistance; nanocarriers
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development and Optimization of Buccal Films Formulations
edited by and Krisztián Pamlényi
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3618 | Submission Open
Keywords: buccal drug delivery; mucoadhesive; polymer films; buccal tablets; solid dosage forms; controlled drug release; fast dissolving formulations; permeability enhancement; pediatric formulations; geriatric formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanocomposites as Implantable Devices or Drug Delivery Platforms: A New Insight into Treat Dental and Oral Diseases submission deadline 28 Feb 2026 | 2 articles | Viewed by 3286 | Submission Open
Keywords: dental implant; covering materials; bone substitutes; scaffold; antioxidant; anti-inflammatory; nanocomposite; controlled release; dental and oral diseases; patches and films; injectable in situ gelling formulations; biocompatibility; tissue regeneration; anticancer
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Novel Drug Delivery Systems for Natural Extracts
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3121 | Submission Open
Keywords: natural extracts; drug delivery systems; pharmacokinetics; liposome; nanoparticles; hydrogel; controlled release; biopharmaceutics; plant extracts; animal products; marine products
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Platform for Tuberculosis Treatment submission deadline 28 Feb 2026 | 2 articles | Viewed by 2886 | Submission Open
Keywords: tuberculosis; anti-TB drugs; drug delivery systems; nanotechnology; bioavailability; targeting
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Inhaled Formulations for Pulmonary Drug Delivery
edited by and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2738 | Submission Open
Keywords: inhaled biologic; inhaled combination therapy; inhaled gene therapy; inhaled nanoparticles; novel inhalable nano-formulation; stability; solubility; smart inhalers; three-dimensional printing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Targeted Therapies and Drug Delivery for Neurodegenerative Diseases
edited by and Chiara Lucchi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2644 | Submission Open
Keywords: targeted drug delivery; blood– brain barrier; neurodegenerative disease treatment; precision medicine; neuroscience
(This special issue belongs to the Section Drug Targeting and Design)
Innovative Applications of Nanotechnology and Photothermal Therapy in Cancer Treatment and Drug Delivery submission deadline 28 Feb 2026 | 3 articles | Viewed by 2567 | Submission Open
Keywords: photothermal therapy; drug delivery; chemotherapy; nanomaterials; local and systemic delivery; in situ delivery; nanoscale dosage forms; nanomedicine; pre-clinical studies; in vitro models; regulatory affairs
(This special issue belongs to the Section Clinical Pharmaceutics)
3D Printing in Personalized Drug Delivery submission deadline 28 Feb 2026 | 2 articles | Viewed by 2277 | Submission Open
Keywords: 3D printing; personalized medicine; precision medicine; on-demand manufacturing; drug delivery systems; patient-centric formulations; additive manufacturing; controlled release; gastro-retentive and floating dosage forms; multi-drug delivery; regulatory challenges in 3D printing manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advances in Colloidal Drug Delivery Systems
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2106 | Submission Open
Keywords: colloidal drug delivery; liposomes; nanoparticles; micelles; solubility enhancement; bioavailability; targeted delivery; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing Cancer Therapy: Magnetic Nanoparticles for Enhanced Targeted Drug Delivery submission deadline 28 Feb 2026 | 2 articles | Viewed by 1954 | Submission Open
Keywords: cancer therapy; drug delivery; magnetic drug targeting; superparamagnetism; hyperthermia; magnetite; ferrite; iron oxide magnetic nanoparticles; superparamagnetic iron oxide nanoparticles; cytotoxicity; apoptosis; magnetic biosensors; magnetic imaging; theranostics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biodegradable Hydrogels with Potential Biomedical Applications as Drug Delivery Systems
edited by , , and Vanessa Rosciardi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1831 | Submission Open
Keywords: biodegradable and hybrid hydrogels; drug delivery; smart biomaterials; stimuli-sensitive; multi-responsive; self-healing; nanocomposites; targeted release; controlled degradation; natural polymers; functionalization and characterization strategies; renewable materials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Research on Amorphous Drugs
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1446 | Submission Open
Keywords: high-throughput screening; combinatorial chemistry; poorly water-soluble compounds; poor water solubility; bioavailability; innovative preparation methods; amorphous drug formulations; free energy; novel evaluation techniques; advanced predictive models; physical stability; mechanistic insights
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Drug Delivery and Pharmacokinetics in Oral Medicine and Dental Infection, 2nd Edition
edited by Igor Tsesis and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1437 | Submission Open
Keywords: oral drug delivery; dental infection/pain; oral medicine; drug delivery; pharmacokinetics; controlled release; periodontal and endodontic infections
(This special issue belongs to the Section Drug Delivery and Controlled Release)
From Nature to Pharmacy: Advances in Bio-Based Pharmaceutical Formulations submission deadline 28 Feb 2026 | 2 articles | Viewed by 1349 | Submission Open
Keywords: natural products; drug delivery systems; bioactive ingredients; nanotechnology; bioavailability; pharmaceutical formulations; plant-derived compounds; biocompatible carriers
(This special issue belongs to the Section Biopharmaceutics)
Probiotics in Pharmaceutics: Exploring the Therapeutic Potential and Formulation Strategies submission deadline 28 Feb 2026 | 1 articles | Viewed by 993 | Submission Open
Keywords: probiotics; formulation; drug delivery; therapeutic potential; microbiome modulation; nutraceuticals; immunomodulation; clinical trials; regulatory affairs
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanoparticle-Based Drug Formulation for Enhancing Nose-to-Brain Delivery
edited by and Richard Nii Lante Lamptey
submission deadline 28 Feb 2026 | 1 articles | Viewed by 973 | Submission Open
Keywords: nanoparticles; nose-to-brain drug delivery; blood– brain barrier (BBB); central nervous system (CNS); neurodegenerative diseases; targeted therapeutics; non-invasive delivery; intranasal administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Bio-Based Hydrogels: Sustainable and Efficient Drug Delivery Solutions
edited by Vesna V. Panić, Rada Pjanović and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 912 | Submission Open
Keywords: bio-based hydrogel; drug delivery system; hydrogel composites; controlled delivery; targeted delivery; drug loading; drug release kinetics; degradation; administration routes; oral delivery; transdermal delivery; in vitro and in vivo analyses
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 710 | Submission Open
Keywords: non-viral gene delivery; lipid nanoparticle; polymeric carrier; endosomal escape; genome editing delivery
(This special issue belongs to the Section Gene and Cell Therapy)
Drug Delivery Strategies and Novel Approaches for Cancer Treatment submission deadline 28 Feb 2026 | 1 articles | Viewed by 513 | Submission Open
Keywords: nanocarriers; drug delivery; cancer therapy; targeted delivery; drug repurposing; controlled release; nanotechnology; anticancer agents
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Promoting the Therapeutic Potential of Neuroactive Drugs with Lipidic Formulations submission deadline 28 Feb 2026 | Viewed by 378 | Submission Open
Keywords: neurological disorders; nanotechnology; lipidic formulations; brain; pharmacokinetics; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Studies of Protein–Ligand Interactions in the Evaluation of the Biological Activity of Compounds submission deadline 28 Feb 2026 | Viewed by 295 | Submission Open
Keywords: protein-ligand interactions; ADMET properties; biological activity; toxicity; molecular docking; dynamic simulations; enzymes inhibition; drug-receptor binding
(This special issue belongs to the Section Biopharmaceutics)
Challenges and Trends in Geriatric Pharmacotherapy: Pharmacodynamics, Pharmacokinetics, and Personalized Therapeutic Strategies submission deadline 28 Feb 2026 | Viewed by 269 | Submission Open
Keywords: pharmacokinetics; pharmacodynamics; drug– drug interactions; drug monitoring; precision dosing; therapeutic strategies; individualized therapy; personalized medicine
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Recent Advances in Injectable Formulations
edited by René Holm
submission deadline 28 Feb 2026 | Viewed by 267 | Submission Open
Keywords: parenteral; sterile; injectable; lyophillized; intravenous; intramuscular; subcutaneous; long-acting injectables; biologicals; pharmacokinetics
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Population Pharmacokinetics: Where Are We Now?
edited by Su-jin Rhee and
submission deadline 28 Feb 2026 | Viewed by 244 | Submission Open
Keywords: pharmacometrics; population pharmacokinetics; pharmacokinetics/pharmacodynamics; machine learning; model-informed drug development; model-informed dose optimization; special populations; real-world data; personalized therapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advances in Natural Anticancer Formulation submission deadline 28 Feb 2026 | Viewed by 144 | Submission Open
Keywords: cancer treatment; phytocompounds; drug formulations; natural-based therapies; in vitro and ex vivo toxicity evaluation; in vivo drug sensitivity; in silico models; pharmacokinetics/pharmacodynamics; innovations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Manipulation of the Blood–Brain Barrier for CNS Drug Delivery Enhancement
edited by David Fortin and
submission deadline 28 Feb 2026 | Viewed by 144 | Submission Open
Keywords: blood– brain barrier (BBB); intra-arterial infusion; BBB manipulation; efflux transporters; CNS delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoparticles in Photodynamic Therapy
edited by , Manuel Francisco Melendrez Castro and
submission deadline 28 Feb 2026 | Viewed by 138 | Submission Open
Keywords: photodynamic therapy (PDT); photosensitizer-loaded nanoparticles; stimuli-responsive nanocarriers; enhanced photosensitizers; antimicrobial photodynamic therapy (aPDT); light-activated nanomedicine; dermatological phototherapy; ocular photodynamic applications; oral infectious diseases
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology for the Prevention, Diagnosis, and Therapy of HIV, HCV, and Coinfection: From Bench to Bedside submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open
Keywords: dendrimers; diagnostics; drug resistance; HCV; HIV; HIV/HCV coinfection; liposomes; nanocarriers; nanoparticles; nanoplatforms; nanotechnology; prevention; targeted drug delivery; therapeutic
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
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