Solid Dispersions for Drug Delivery: Development, Preparation and In Vitro/In Vivo Characterization
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 636
Special Issue Editor
Interests: solid dispersions; lipid carriers; low solubility; pharmaceutical technology; topical drug delivery; formulation and characterization of dosage forms; drug release; skin permeation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Solid dispersion is one of the effective approaches for drugs characterized by poor solubility. Many polymers with various physicochemical and thermochemical properties are utilized to prepare the solid dispersions, in which drugs can be dispersed as separate molecules, amorphous particles, or crystalline particles in the crystalline or amorphous carrier. Numerous studies on solid dispersions have been published and have shown the many advantageous of solid dispersions in enhancing drug solubility, improving stability and modifying its release. These advantages include reducing particle size and enhancing wettability and porosity, as well as changing the drug crystalline state, preferably into the amorphous state. Solid dispersions can be prepared by various methods, e.g., solvent evaporation, spray drying, hot melt extrusion, ball milling, freeze-drying or electrospinning, and then can be examined using different analytical and instrumental methods to assess their features (solubility, dissolution rate, physical state of drug, stability, drug–polymer interactions, morphology).
We are pleased to invite you to submit articles on the latest advances in solid dispersions for drug delivery. In the submitted article, readers will find new information about solid dispersions, focusing on their development, preparation, stability assessment and evaluation of their properties. Studies offering innovative methodologies, use of novel polymers and new applications of solid dispersions are highly welcome.
We look forward to receiving your contributions.
Dr. Anna Czajkowska-Kośnik
Guest Editor
Manuscript Submission Information
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Keywords
- solid dispersion
- poorly soluble drugs
- stability
- dissolution properties
- molecular interaction
- polymers
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