Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ionic Liquids in Pharmaceutical and Biomedical Applications, 2nd Edition
edited by
submission deadline 30 May 2025 | 4 articles | Viewed by 13969 | Submission Open
Keywords: ionic liquids; deep eutectic solvents; active pharmaceutical ingredients (API); drug delivery systems; antimicrobial properties; drug and protein stabilization; nanoformulations; biosensing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Application Prospects and Challenges of Cell-Penetrating Peptides in Drug Delivery Systems
edited by
submission deadline 30 May 2025 | 3 articles | Viewed by 6557 | Submission Open
Keywords: cell-penetrating peptide; peptide conjugate; cellular uptake; structure-activity relationship; drug-delivery systems
(This special issue belongs to the Section Gene and Cell Therapy)
Development of New Nanotechnological Systems Loaded with Drugs for Infectious Disease Application
edited by , Marlus Chorilli and Taís Maria Bauab
submission deadline 30 May 2025 | 4 articles | Viewed by 4882 | Submission Open
Keywords: nanosystems; controlled drug release; infectious diseases; microbial resistance; pathogenic microorganism; drug delivery systems; nanotechnology; nanotherapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Computer-Aided Development: Recent Advances and Expectations
edited by Alan Talevi
submission deadline 30 May 2025 | 3 articles | Viewed by 4720 | Submission Open
Keywords: ADME; ADMET; antitarget; drug design; computer-aided drug design; computer-assisted drug design; computer-guided drug design; ligand-based approaches; machine learning; deep learning; de novo drug design; fragment-based drug design; avatar clinical research
(This special issue belongs to the Section Drug Targeting and Design)
In Vitro–In Vivo Correlation and Mechanistic Pharmacokinetic Models: Bridging Drug In Vitro Characteristics and In Vivo Behaviors
edited by Zhijun Kevin Wang
submission deadline 30 May 2025 | 2 articles | Viewed by 1795 | Submission Open
Keywords: IVIVC; PBPK; pharmacokinetic modeling; mechanistic modeling; drug development; drug– drug interactions; sensitivity analysis; pharmacometrics
(This special issue belongs to the Section Clinical Pharmaceutics)
Exploring Solid Dosage Forms: Characterization, Dissolution, and Stability
edited by Magali B. Araújo
submission deadline 30 May 2025 | 1 articles | Viewed by 598 | Submission Open
Keywords: solid dosage forms; drug release kinetics; physicochemical properties; dissolution testing; stability assessment; crystalline forms; pharmaceutical formulations; analytical methods
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Ultrasound-Mediated Brain Drug Delivery
edited by Muna Aryal
submission deadline 30 May 2025 | Viewed by 388 | Submission Open
Keywords: low-intensity transcranial focused ultrasound; blood-brain opening; neuromodulation; glymphatic perturbation; brain diseases: brain cancer; aging; and Alzheimer; ultrasound-sensitive biomaterials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Development of Physiologically Based Pharmacokinetic (PBPK) Modeling submission deadline 31 May 2025 | 5 articles | Viewed by 11492 | Submission Open
Keywords: physiologically based pharmacokinetic modeling (PBPK); modeling and simulations (M& S); pharmacokinetics; ADME; pharmacometrics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nano-Drug Delivery Systems for Targeting the Tumor Microenvironment and Simultaneously Overcoming Drug Resistance Properties submission deadline 31 May 2025 | 4 articles | Viewed by 9313 | Submission Open
Keywords: cancer therapy; multidrug resistance; mechanisms of drug resistance; tumor microenvironment; ABC transporters; combined therapy; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in the Use of Ultrasound to Enhance Drug Delivery and Efficacy for the Treatment of Cancer submission deadline 31 May 2025 | 3 articles | Viewed by 8221 | Submission Open
Keywords: therapy ultrasound; HIFU; drug delivery; sonodynamic therapy; cancer treatment; histotripsy; hyperthermia; thermal ablation; cavitation; blood– brain barrier
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Lipid/Polymer-Based Drug Delivery Systems
edited by and Xiuge Gao
submission deadline 31 May 2025 | 3 articles | Viewed by 5204 | Submission Open
Keywords: lipid-based nanomaterials; polymer-based nanoparticles; lipid/polymer hybrid nanoparticles; targeted drug delivery; antimicrobial application; wound healing; cancer therapy; mRNA vaccines; transdermal delivery; oral administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Fluorescent Probes as a Tool in Diagnostic and Drug Delivery
edited by Leo Zhang, and Peng Zheng
submission deadline 31 May 2025 | 2 articles | Viewed by 3420 | Submission Open
Keywords: fluorescent probes; diagnostics; drug delivery; imaging techniques; biosensing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Polymer- and Lipid-Based Nanostructured Drug Delivery Systems for the Treatment of CNS Diseases: Recent Advances towards Clinical Application, 2nd Edition submission deadline 31 May 2025 | 2 articles | Viewed by 3379 | Submission Open
Keywords: neurodegenerative diseases; neurological diseases; brain tumors; brain targeting; nose-to-brain delivery; polymers from natural and renewable resources; polymer/lipid nanoparticles; neurotrophic factors; stem cells; exosomes
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Inhibitors for Targeted Therapies
edited by Anke Wilhelm
submission deadline 31 May 2025 | 4 articles | Viewed by 2573 | Submission Open
Keywords: targeted therapy; emerging technologies; antiviral strategies; inhibitor development; molecular targets; precision medicine; drug R& D dynamics; pharmaceutics; drug resistance
(This special issue belongs to the Section Drug Targeting and Design)
Mathematical Modeling of Polymer-Based Drug Delivery Systems: Mechanisms and Applications
edited by
submission deadline 31 May 2025 | 1 articles | Viewed by 1845 | Submission Open
Keywords: polymers; drug delivery; mathematical model; experimental data
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drugs in Dermatology: Topical Agent, Cosmeceuticals, Dermatological Drug Delivery, Natural Product in Dermatology, 2nd Edition
edited by
submission deadline 31 May 2025 | 1 articles | Viewed by 1368 | Submission Open
Keywords: skin disease; dermatological drugs; topical agent; cosmeceuticals; natural products; drug targeting; functional ingredients; skin aging; hair regrowth
(This special issue belongs to the Section Drug Targeting and Design)
Conjugated Polymer Nanoparticles: Innovative Designs for Photodynamic and Photothermal Therapy in Cancer and Bacterial Infections—Preclinical Evaluation and Beyond
edited by
submission deadline 31 May 2025 | 2 articles | Viewed by 1303 | Submission Open
Keywords: conjugated polymer nanoparticles; organic semiconducting materials; biomedical application; drug delivery; preclinical evaluation; antimicrobial nanoparticles; antitumoral nanoparticles
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Drug Delivery Systems for Transmucosal Routes Applied in the Treatment of Infectious and Chronic Degenerative Diseases
edited by Fernanda Isadora Boni
submission deadline 31 May 2025 | 1 articles | Viewed by 940 | Submission Open
Keywords: mucosal permeation; drug delivery system development; biological behavior; mucoadhesion; mucopermeation; mucosal route of administration
(This special issue belongs to the Section Drug Targeting and Design)
New Strategies in Gene and Cell Therapy for Neurological Disorders
edited by
submission deadline 31 May 2025 | 1 articles | Viewed by 918 | Submission Open
Keywords: gene and cell therapy; neurodegenerative diseases; neurodevelopmental disorders; neuropsychiatric conditions; CNS tumors; trauma and injury in the CNS; blood– brain barrier; neuroimmunology and immunomodulation; peripheral nervous system disorders; regenerative medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Advances in Antiparasitic Agents
edited by Juan José García-Rodríguez
submission deadline 31 May 2025 | 1 articles | Viewed by 817 | Submission Open
Keywords: parasites; parasitic diseases; drug combinations; antiparasitic activity; pharmacokinetics; drug resistance; mechanism of action; formulations; drug synthesis and discovery
(This special issue belongs to the Section Drug Targeting and Design)
Natural Macromolecule-Based Nanocarriers for Drug Delivery
edited by
submission deadline 31 May 2025 | 1 articles | Viewed by 789 | Submission Open
Keywords: macromolecules; polysaccharides; proteins; nucleic acids; lipids; nanocarrier; drug delivery; targeted delivery; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Delivery Systems for Ocular Diseases submission deadline 31 May 2025 | 1 articles | Viewed by 678 | Submission Open
Keywords: ocular diseases; contact lens delivery; drug delivery systems; nanotechnology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements in AI and Pharmacokinetics
edited by
submission deadline 31 May 2025 | 1 articles | Viewed by 587 | Submission Open
Keywords: AI in nanomedicine; drug targeting; pharmacokinetics; pharmacodynamics; drug– receptor interactions
(This special issue belongs to the Section Drug Targeting and Design)
Novel Carriers for Drug Delivery and Brain Disease Treatment Across the Blood-Brain Barrier
edited by and Ana R. Santa-Maria
submission deadline 31 May 2025 | Viewed by 427 | Submission Open
Keywords: novel carriers; drug delivery; blood– brain barrier (BBB); carrier technologies; transformative therapies; neurological disorders
(This special issue belongs to the Section Drug Delivery and Controlled Release)
3D/4D/5D Printing of Medicines and Medical Devices submission deadline 31 May 2025 | Viewed by 368 | Submission Open
Keywords: 3D printing; 4D printing; 5D printing; personalized therapies; novel printing inks
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advancements and Innovations in Antibody Drug Conjugates
edited by , Shivaji Edupuganti and Ebaston Thankarajan
submission deadline 31 May 2025 | Viewed by 322 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Antimicrobial Drug Delivery Strategies
edited by Zhixin Lei
submission deadline 31 May 2025 | Viewed by 249 | Submission Open
Keywords: antimicrobial; drug delivery; drug formulations; drug target; drug development
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances and Challenges in Nanomedicine: Translating Nanotechnology into Therapeutics for Cancer, Neurodegenerative, and Infectious Diseases submission deadline 31 May 2025 | Viewed by 233 | Submission Open
Keywords: nanomedicine; targeted delivery; gene therapies; immunotherapies; cancer; infectious diseases; neurological disorders
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Anticancer Drug Metabolism Research: Implications for Personalized Therapeutics submission deadline 31 May 2025 | Viewed by 215 | Submission Open
Keywords: anticancer drug metabolism; personalized medicine; drug interactions; therapeutic efficacy; drug safety; pharmacogenomics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
edited by and Daniel De Vos
submission deadline 31 May 2025 | Viewed by 206 | Submission Open
Keywords: phage vector; drug delivery; phage therapy; phage technology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biomedical Applications of Chitosan-Based Biomaterials submission deadline 31 May 2025 | Viewed by 194 | Submission Open
Keywords: chitosan; biocompatible polymers; biomaterials; biomedical applications; tissue engineering; drug delivery systems; regenerative medicine; wound healing; antimicrobial properties; cancer therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Multifunctional Nanomaterials in Drug Delivery
edited by
submission deadline 31 May 2025 | Viewed by 190 | Submission Open
Keywords: nanomaterials; bioavailability; targeting efficiency; controlled release; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Cationic Nanoparticles for Vaccine Delivery: Design, Mechanisms, and Applications submission deadline 31 May 2025 | Viewed by 182 | Submission Open
Keywords: cationic nanoparticles; vaccine delivery systems; adjuvants; antigen presentation; nanoparticle synthesis; immune modulation; toxicity and biocompatibility; nucleic acid vaccines; protein-based vaccines; nanoparticle– immune cell interaction; surface functionalization; biodegradability; translational challenges; systems biology
(This special issue belongs to the Section Biologics and Biosimilars)
Peptide Polymer Delivery Systems for Antibacterial and Immunomodulatory Applications
edited by Hashem Etayash
submission deadline 31 May 2025 | Viewed by 157 | Submission Open
Keywords: antimicrobial peptides; host defense peptides; bacterial infection; biofilms; immunomodulatory agents; drug resistance; antibiotics; surafe-tethered peptides; peptide formulation; peptide polymers
(This special issue belongs to the Section Biologics and Biosimilars)
Nanoparticle-Based mRNA Vaccines
edited by , Yonger Xue and
submission deadline 31 May 2025 | Viewed by 144 | Submission Open
Keywords: messenger RNA (mRNA); nanoparticles; mRNA vaccines; lipid nanoparticles (LNPs); immunotherapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
A New Generation of Metal Anticancer Drugs
edited by
submission deadline 31 May 2025 | Viewed by 143 | Submission Open
Keywords: metal-based drugs; cytotoxicity; cancer; nanoparticles; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Functional Hydrogels in Drug Delivery and Tissue Repair: Synergistic Strategies for Regenerative Therapies
edited by Huilong Guo
submission deadline 31 May 2025 | Viewed by 116 | Submission Open
Keywords: hydrogel; drug delivery; wound healing; controlled drug release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmaceutical Solids: Advanced Manufacturing and Characterization
edited by Vivek Verma
submission deadline 10 Jun 2025 | 12 articles | Viewed by 25623 | Submission Open
Keywords: hot melt extrusion (HME); nanotechnology (nanoparticles and nanosuspensions; nanoprecipitation and nano emulsification); three-dimensional printing; spray drying including supercritical CO2-assisted spray drying; quality-by-design (QbD) approach; continuous manufacturing; artificial intelligence and machine learning; template/surface assisted crystallisation; microwave assisted manufacturing; sono precipitation; mechanochemistry; advanced characterizations such as X-Ray Diffraction (XRD); Differential Scanning Calorimetry (DSC); Scanning Electron Microscopy (SEM); Raman Spectroscopy; Dynamic Vapor Sorption (DVS); Inverse Gas Chromatography (IGC); Quartz Crystal Microbalance (QCM); scanning white light interferometry; TOF-SIMS; XPS; Solid State Nuclear Magnetic Resonance; in situ PXRD; TEM; and SEM; SEM-Raman; and other solid state characterizations; hyperspectral imaging; MRI characterization of solid pharmaceutical dosage forms; X-ray tomography and terahertz pulsed spectroscopy and imaging; NIR spectroscopy; Process Analytical Technology (PAT)
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Application of Nanoparticles and Dendrimers for Treating Infectious Diseases submission deadline 10 Jun 2025 | 8 articles | Viewed by 22342 | Submission Open
Keywords: dendrimers  ; infectious diseases  ; antiviral  ; antibacterial  ; antiparasitic  ; antifungal  ; nanoparticles
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Parenteral Formulations submission deadline 10 Jun 2025 | 5 articles | Viewed by 16835 | Submission Open
Keywords: nanoparticle; drug interactions; nanoemulsions and submicron emulsions; drug carriers; drug compatibility; parenteral nutrition
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Mechanisms of Drug Interactions: Pharmacodynamics and Pharmacokinetics submission deadline 10 Jun 2025 | 6 articles | Viewed by 7912 | Submission Open
Keywords: drug interactions; pharmacokinetics; pharmacodynamics; ADME
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Peptide–Drug Conjugates for Targeted Delivery submission deadline 10 Jun 2025 | 3 articles | Viewed by 4993 | Submission Open
Keywords: Peptide– Drug Conjugate (PDC); peptide; targeted therapy; bioconjugate; prodrug
(This special issue belongs to the Section Drug Targeting and Design)
Application of Nanostructured Lipid Carriers in Antibacterial and Anticancer submission deadline 10 Jun 2025 | 1 articles | Viewed by 2329 | Submission Open
Keywords: nanostructured lipid carriers; antibacterial therapy; anticancer therapy; drug delivery; pharmaceutical nanotechnology; targeted delivery; drug resistance; clinical evaluation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Pharmaceutical Science and Technology in Spain submission deadline 10 Jun 2025 | Viewed by 442 | Submission Open
Keywords: Spanish scientists; pharmaceutical technology; innovation; drug delivery; precision medicine; research; advancements; healthcare
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Delivery Strategy Based on Magnetic Nanoparticles for Disease Treatment
edited by and Samuel Maritim
submission deadline 10 Jun 2025 | Viewed by 431 | Submission Open
Keywords: nanoparticle with magnetic core and drug loading capability; magnetic contrast agents in Magnetic Resonance Imaging (MRI) and Magnetic Particle Imaging (MPI); magnetic nanoparticle as hyperthermia agents for cancer tumor therapy; magnetic vectors which can be directed by magnetic field for targeted drug delivery; magnetic nanoparticles conjugated with drugs; ligands; or antibodies for specific delivery; magnetic nanoparticle designs to obtain medical breakthroughs in diagnosis; and drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Extracellular Vesicle for Drug Delivery
edited by
submission deadline 10 Jun 2025 | 1 articles | Viewed by 300 | Submission Open
Keywords: estracellular vesicle; exosomes; drug delivery; behavior; uptake; quantification; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology Applied in Prevention, Diagnosis and Treatment of Cancer
edited by
submission deadline 20 Jun 2025 | 10 articles | Viewed by 26794 | Submission Open
Keywords: nanoparticles; drug delivery; biosensors; imaging; theragnosis
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Novel Drugs, Targets and Therapies Against Infectious Diseases submission deadline 20 Jun 2025 | 7 articles | Viewed by 17415 | Submission Open
Keywords: infectious diseases; immunotherapy; vaccines; nanotechnology; drug formulation; targets; biological therapies
(This special issue belongs to the Section Drug Targeting and Design)
Pharmaceutical Applications of Metal Complexes and Derived Materials submission deadline 20 Jun 2025 | 5 articles | Viewed by 6336 | Submission Open
Keywords: metallodrugs; metal complexes in cancer treatment; metal complexes as antimicrobial agents; delivery systems containing metal complexes; metal complexes in photodynamic therapy; metal complexes in biosensors; metal complexes as biomarkers; radiopharmaceuticals; computational studies in metallodrugs development; mechanism of action of bioactive metal complexes
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advancements in the 3D Printing of Pharmaceutics
edited by L. R.Jaidev Chakka
submission deadline 20 Jun 2025 | 1 articles | Viewed by 1821 | Submission Open
Keywords: 3D printing; pharmaceutics; AI/ML; drug formulations; 3D printing methods.
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
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