Exploring Solid Dosage Forms: Characterization, Dissolution, and Stability
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: 30 May 2025 | Viewed by 433
Special Issue Editor
Special Issue Information
Dear Colleagues,
Solid dosage forms, such as tablets and capsules, represent a cornerstone of pharmaceutical formulations, playing a critical role in drug delivery systems. These forms significantly influence drug release kinetics, bioavailability, absorption, and overall therapeutic efficacy. The characterization of solid dosage forms involves a comprehensive analysis of their physicochemical properties, including solubility, stability, and solid-state characteristics, which are essential for ensuring optimal performance in vivo. Recent advancements in analytical methodologies for assessing dissolution profiles, intrinsic dissolution rates, and solid-state transitions have proven pivotal in elucidating the pharmacokinetics of active pharmaceutical ingredients (APIs). Moreover, the interplay between formulation variables and environmental conditions, as exemplified by studies on phase transitions and solubility behaviors of various crystalline forms, highlights the complexity of solid dosage forms.
This Special Issue aims to compile high-quality research articles and reviews that explore the characterization, dissolution, and stability of solid dosage forms, addressing both fundamental principles and applied methodologies in the field. We invite researchers to contribute their findings and insights into this critical field of study, enhancing our collective understanding of solid dosage forms.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Phase transitions and solubility studies of various crystalline forms;
- Quality evaluation of water samples used in pharmaceutical compounding;
- Application of multivariate optimization strategies in analytical method validation;
- Solid-state characterization and stability assessments of novel compounds;
- Dissolution studies emphasizing the discriminatory power of assays for various drug formulations;
- Comprehensive reviews on analytical methods for quantification of drugs in solid dosage forms.
I look forward to receiving your contributions that will enrich this Special Issue and advance our understanding of solid dosage forms in pharmaceutical sciences.
Prof. Dr. Magali B. Araújo
Guest Editor
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Keywords
- solid dosage forms
- drug release kinetics
- physicochemical properties
- dissolution testing
- stability assessment
- crystalline forms
- pharmaceutical formulations
- analytical methods
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