Peptide Polymer Delivery Systems for Antibacterial and Immunomodulatory Applications
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 175
Special Issue Editor
Special Issue Information
Dear Colleagues,
Peptides' unique structural diversity, wide range of activity, accepted biocompatibility, and minimal propensity to develop resistance are the driving forces behind their advancement as antimicrobial therapeutics. Naturally produced and synthetic peptide polymers are promising antimicrobial agents and anti-biofilms, biocatalysts, receptors on solid substrates, bioactive materials in medical devices, wound dressings, food packaging, etc. The evolution of these polymers as immunomodulators has also made them extremely useful intrinsic boosters of infection-resolving immunity and inflammatory inhibitors.
In the realm of drug delivery, peptide polymers offer a cutting-edge approach to overcoming challenges associated with the stability and efficacy of therapeutic agents. Their integration with advanced biomaterials and printing techniques, such as 3D printing, is revolutionizing the creation of smart, stimuli-responsive systems and personalized medical devices. This technology allows for the precise placement of antimicrobial peptides (AMPs) within these devices, enhancing their bioavailability and reducing the likelihood of resistance development.
In this Special Issue, we aim to promote significant research in peptide polymers and signify their progress and promising future in drug delivery and pharmaceutical applications. We also seek to capture the limitations that hinder their quick movement to the marketplace while addressing strategies to resolve those shortcomings. Original research, brief communications, review articles, prospectives, and others on all aspects of antimicrobial peptides (AMPs) or host defense peptides (HDPs) are welcome.
We look forward to receiving your contributions.
Dr. Hashem Etayash
Guest Editor
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Keywords
- antimicrobial peptides
- host defense peptides
- bacterial infection
- biofilms
- immunomodulatory agents
- drug resistance
- antibiotics
- surafe-tethered peptides
- peptide formulation
- peptide polymers
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