Advances in Analytical Method Development for Pharmaceutical Formulations
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 137
Special Issue Editors
Interests: pharmaceutical analysis; spectroscopic analysis; X-ray powder diffraction; hyperspectral micro-raman imaging; solid state characterization; particle size determination
Interests: Raman spectroscopy; Raman imaging; IR spectroscopy; IR imaging; X-ray fluorescence; atomic absorption spectrometry; X-ray diffraction; optical microscopy; micro-computer tomography; pharmaceuticals; bone; cartilage
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The analysis of pharmaceutical formulations often presents multiple challenges, particularly in the detection, identification, characterization, and quantification of active pharmaceutical ingredients (APIs). In recent years, the introduction of increasingly sophisticated pharmaceutical products has underscored the need for advanced analytical methods even further. Developing an appropriate sample preparation strategy and selecting the most suitable analytical technique are critical to overcoming these challenges effectively.
Chromatographic techniques remain fundamental tools for the separation, identification, and quantification of APIs and impurities in pharmaceutical formulations, thereby ensuring the quality, stability, and safety of the final products. Additionally, solid-state characterization and particle size distribution (PSD) analysis of APIs are crucial for achieving the desired physical properties, bioavailability, and overall product performance. Techniques such as X-ray diffraction (XRD), Raman and infrared (IR) spectroscopy, solid-state nuclear magnetic resonance (ss-NMR), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), laser diffraction, and optical microscopy or scanning electron microscopy (SEM) are frequently employed for these purposes.
This Special Issue aims to highlight the latest advancements in analytical method development, covering both sample preparation and instrumental techniques. Original research articles, short communications, and review papers are welcome. Suggested topics include, but are not limited to: novel chromatographic methods for pharmaceutical analysis, solid-state characterization of APIs, identification of novel polymorphs, quality control and stability studies of pharmaceutical formulations, API–excipient interactions, quantitative challenges in complex formulations, physicochemical studies of pharmaceutical formulations, and PSD determination in solid, semi-solid, and suspension-based systems.
Dr. Michail Lykouras
Dr. Malvina Orkoula
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmaceutical analysis
- sample preparation
- chromatographic techniques
- solid-state characterization
- particle size determination
- vibrational spectroscopy
- X-ray diffraction
- thermal techniques
- microscopy
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