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Special Issue "Nutrition and Epigenetics"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: 10 December 2019.
Interests: epigenetics; genetic variability; aging; molecular health biomarkers
Interests: epigenetics; aging; statistical genetics
Epigenetics has been rapidly arising as a major topic in molecular biology and genetics. Nutrition is certainly among the most important external factors influencing the epigenetic profile. Pioneering studies have shown the importance of nutrition in modulating the fate of different organisms, such as honey bees and rodents. More recently, the long-term effects of diet on gene expression variations are increasingly recognized as major regulators that influence the phenotypic plasticity, as well as health and lifespan, via epigenetic modifications. In mammals, nutrient availability has been shown to induce epigenetic modifications at both global and locus-specific levels through a variety of molecular mechanisms, which mainly involve mitochondrial activity. More particularly, the bioavailability of S-adenosylmethionine (SAM), the substrate for the methyltransferase reactions, is regulated by the dietary intake of vitamin B2, B6, and B12. Therefore, studies carried out, mostly in rodents, revealed that a diet deficient in or supplemented with methyl donors is responsible for global DNA hypo-methylation and hyper-methylation, respectively. In addition, calorie restriction (CR), namely the reduction of food intake widely recognized to extend longevity in different species, leads to aberrant DNA methylation patterns by modulating DNMT activities.
In this Issue of Nutrients, we would like to gather papers dealing with the interaction between nutrition and epigenetic modifications, in particular, DNA methylation modifications. Our aim is to outline the state-of-the-art on this field and to bring to the attention of the readers the issues that will be the most important topics in the near future.
Prof. Giuseppe Passarino
Prof. Dr. Alberto Montesanto
Prof. Dr. Dina Bellizzi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Dietary habits
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Author: Paolo Garagnani
Affiliation: Department of Experimental, Diagnostic, and Specialty Medicine (DIMES), University of Bologna, Italy
Title: Epigenetic readouts of dietary interventions
Author: Mauro Provinciali
Affiliation: Italian National Research Center on Ageing (INRCA), Ancona, Italy
Title: Circulating markers of nutritional status and CpG DNA methylation in young and elderly subjects
Author: Giuseppe Passarino
Affiliation: Department of Biology, Ecology and Earth Science, University of Calabria, Rende, Italy
Title: Tissue specific epigenetic modifications of mitochondrial correlated genes in relation to aging and diet
Author: Celine Tiffon
Affiliation: French National Cancer Institute, Boulogne-Billancourt, France
Title: Nutrition-related epigenetic modifications: characterization on metabolism, aging and health status