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  • Article
  • Open Access
113 Views
11 Pages

Psychometric Validation of the Arabic Version of the WPAI:Migraine Questionnaire in Patients with Migraine

  • Abdulrazaq Albilali,
  • Rema A. Almutawa,
  • Elaf A. Almusahel,
  • Renad A. Almutawa,
  • Nasser A. Almutawa,
  • Faisal M. Almutawa,
  • Shiekha AlAujan and
  • Haya M. AlMalag

12 December 2025

Background: Migraine is a highly prevalent neurological disorder and a leading cause of disability, particularly among working-age adults. Although the Work Productivity and Activity Impairment (WPAI) questionnaire is widely used to assess the functi...

  • Article
  • Open Access
91 Views
16 Pages

Thenar Muscle Atrophy: Clinical, Electrodiagnostic, and Ultrasound Features in 197 Patients

  • Lisa B. E. Shields,
  • Vasudeva G. Iyer,
  • Stephen Furmanek,
  • Yi Ping Zhang and
  • Christopher B. Shields

11 December 2025

Background/Objectives: Atrophy of the thenar muscles (abductor pollicis brevis [APB], opponens pollicis [OP], and flexor pollicis brevis [FPB]) is most commonly caused by carpal tunnel syndrome (CTS). It may also occur following injury to the recurre...

  • Article
  • Open Access
164 Views
16 Pages

Serum Aquaporin-4 Antibody Status and TGF-β in Neuromyelitis Optica Spectrum Disorder: Impact on Astrocyte Function and Correlation with Disease Activity and Severity

  • Vinicius Gabriel Coutinho-Costa,
  • Isadora Matias,
  • Renan Amphilophio Fernandes,
  • Michele Siqueira,
  • Larissa Araujo Duarte,
  • Beatriz Martins Fernandes,
  • Jorge Marcondes de Souza,
  • Soniza Vieira Alves-Leon and
  • Flávia Carvalho Alcantara Gomes

9 December 2025

Background: Neuromyelitis optica spectrum disorder (NMOSD) involves demyelinating astrocytopathy. Most cases have autoantibodies against aquaporin-4 (AQP4 ab), but AQP4 ab-negative patients may also meet NMOSD criteria. Overlapping clinical phenotype...

  • Article
  • Open Access
162 Views
14 Pages

Rare Variants of Immune-Related Genes Increase Susceptibility to Autoimmune Encephalitis: An Association Study

  • Chih-Hsiang Lin,
  • Shiau-Ching Chen,
  • Chen-Jui Ho,
  • Che-Wei Hsu,
  • Shih-Ying Chen,
  • Yan-Ting Lu and
  • Meng-Han Tsai

8 December 2025

Introduction: Autoimmune encephalitis (AE) is a neurological disorder caused by immune responses targeting neuron-surface or synaptic proteins. While its immunological mechanisms have been studied, the genetic underpinnings remain unclear. This study...

  • Systematic Review
  • Open Access
223 Views
14 Pages

8 December 2025

Background/Objectives: The optimal timing for initiating oral anticoagulants (OACs) after acute ischemic stroke (AIS) in patients with atrial fibrillation (AF) remains uncertain due to potential risks of recurrent stroke and bleeding. This meta-analy...

  • Systematic Review
  • Open Access
510 Views
18 Pages

2 December 2025

Background: Neurodegenerative diseases remain a central topic in biomedical research, with Alzheimer’s disease (AD) being the most extensively studied. Recent advances in multi-omics integration, particularly proteomics-based approaches, have e...

  • Review
  • Open Access
274 Views
21 Pages

2 December 2025

Background: Alzheimer’s Disease (AD) is the most common form of dementia and is characterized by progressive cognitive decline and neurodegeneration. In Italy, AD represents a major public health and socio-economic challenge. This review aims t...

  • Article
  • Open Access
236 Views
35 Pages

Predicting Quality of Life in Relapsing–Remitting Multiple Sclerosis: Clinical Burden Meets Emotional Balance in Early Disease

  • Emilio Rubén Pego Pérez,
  • María Lourdes Bermello López,
  • Eva Gómez Fernández,
  • María del Rosario Marín Arnés,
  • Mercedes Fernández Vázquez,
  • María Irene Núñez Hernández and
  • Emilio Gutiérrez García

1 December 2025

Background/Objectives: Relapsing-remitting multiple sclerosis (RRMS) is a chronic neurological disease that significantly impacts health-related quality of life (HRQoL). This study aimed to analyze the evolution of HRQoL in individuals with RRMS, ide...

  • Case Report
  • Open Access
224 Views
8 Pages

Influenza B-Associated Mild Encephalopathy with Reversible Splenial Lesion in an Adult: A Case Report

  • Nicodemus Edrick Oey,
  • Moe Pearl Shwe,
  • Alvin Dingyuan Wang and
  • Andrew Che Fai Hui

30 November 2025

Background/Objectives: Mild Encephalopathy with Reversible Splenial Lesion (MERS) is a potential complication of certain viral infections, but adult cases involving influenza are rare in the literature. Here, we report a case of a 31-year-old Chinese...

  • Article
  • Open Access
205 Views
17 Pages

Gender Differences in Subacute Post-Stroke Patients During Rehabilitation: Functional, Cognitive, and Nutritional Insights

  • Carola Cocco,
  • Mariacristina Siotto,
  • Alessandro Guerrini,
  • Marco Germanotta,
  • Francesca Falchini,
  • Valeria Cipollini,
  • Laura Cortellini,
  • Arianna Pavan,
  • Stefania Lattanzi and
  • Sabina Insalaco
  • + 4 authors

30 November 2025

Background/Objectives: Despite the well-documented gender differences observed during hospitalisation, research in post-stroke recovery remains limited. This study aims to clarify this topic in subacute post-stroke patients undergoing rehabilitation,...

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Neurol. Int. - ISSN 2035-8377