Toxicity and Ecotoxicity Assessment of Nanomaterials by In Vitro Models

Dear Colleagues,

In the past few decades, significant effort has been devoted to the evaluation of toxicity and ecotoxicity of nanomaterials (NMs), particularly using in vitro models and methods. These models and methods are particularly well suited to explore the mode of action and molecular mechanisms of NM toxicity, but extrapolation to an in vivo situation is sometimes difficult to achieve. Moreover, in vitro systems often suffer from dramatic interference of NMs with assay processes and components.

This Special Issue will cover recent advances in the in vitro development (and use) of cheap and robust assays for NM toxicology assessment, as well as the development of new models that better mimic the in vivo situation, including 3D cell and/or organoid models and long-term/low-dose exposure scenarios. Models that better mimic the environment, such as mesocosms, or systems encompassing soil and plants or soil, bacteria, and plants, and the flow and fate of NMs in these systems are also included. Finally, any in vitro study describing mechanistic insight into the toxicological and ecotoxicological mode of action of NMs, which may be either potential environmental pollutants, nanodrug systems, or nanobiomaterials, is also in the scope of this Special Issue.

Dr. Marie Carriere
Dr. Camille Larue
Guest Editors

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