Current Trends in Nanoscale Magnetism

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Nanocomposite Materials".

Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 4912

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Department of Physics, Villanova University, Villanova, PA 19085, USA
Interests: magnetic materials; condensed matter physics; nanomaterials
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Dear Colleagues,

Nanomagnetism is an ever-expanding field that has witnessed great scientific advancement over the past two decades. The synthesis of novel magnetic nanomaterials, the exploration of associated magnetic phenomena, and the characterization techniques and applications in diverse areas of nanotechnology continue to make important new inroads.

For this Special Issue, both new scientific contributions and review articles are being solicited on the synthesis, characterization, and application of 0D, 1D, 2D, and 3D magnetic nanostructures. The ability to characterize their static and dynamic magnetic properties, on a wide range of timescales, is fundamental to understanding the underlying physics responsible for their behavior. Novel behavior arises from the surface and interface effects of non-collinear spin structures because of spatial confinement, the spin coupling of different magnetic phases across phase boundaries, interparticle interactions, and tunable magnetoresistive and superparamagnetic properties. Magnetophoretic technologies in the bio-medical field have tremendously advanced biomolecule and cell separation methodologies, magnetically-guided drug delivery, gene delivery, and transfection. Within the magnetophoretic platform, superparamagnetic iron oxide nanoparticle (SPION) carriers have been developed as bifunctional agents for disease diagnosis and therapy.

Full articles, communications, and reviews on these and related areas exploring the fundamental physics and applications of nanomagnetism will be considered.

Prof. Dr. Georgia C. Papaefthymiou
Guest Editor

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Published Papers (1 paper)

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16 pages, 4719 KiB  
Article
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
by Valentin Nica, Carlos Caro, Jose Maria Páez-Muñoz, Manuel Pernia Leal and Maria Luisa Garcia-Martin
Nanomaterials 2020, 10(5), 907; https://doi.org/10.3390/nano10050907 - 8 May 2020
Cited by 34 | Viewed by 4542
Abstract
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic [...] Read more.
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic agents for magnetic hyperthermia and magnetic resonance imaging (MRI). These nanosystems have been thoroughly characterized by X-ray Diffraction (XRD), Transmission Electron Miscroscopy (TEM), Dark Field-TEM (DF-TEM), Vibrating Sample Magnetometry (VSM), and inductive heating, in order to elucidate their structure, morphology, and magnetic properties. The bi-magnetic CoFe2O4@ZnFe2O4 and CoFe2O4@MnFe2O4 nanoparticles (NPs) exhibited a core-shell structure with a mean average particle size of 11.2 ± 1.4 nm and 14.4 ± 2.4 nm, respectively. The CoFe2O4@MnFe2O4 NPs showed the highest specific absorption rate (SAR) values (210–320 W/g) upon exposure to an external magnetic field, along with the highest saturation magnetization (Ms). Therefore, they were selected for functionalization with the PEGylated ligand to make them stable in aqueous media. After the functionalization process, the NPs showed high magnetic relaxivity values and very low cytotoxicity, demonstrating that CoFe2O4@MnFe2O4 is a good candidate for in vivo applications. Finally, in vivo MRI experiments showed that PEGylated CoFe2O4@MnFe2O4 NPs produce high T2 contrast and exhibit very good stealth properties, leading to the efficient evasion of the mononuclear phagocyte system. Thus, these bi-magnetic core-shell NPs show great potential as theranostic agents for in vivo applications, combining magnetic hyperthermia capabilities with high MRI contrast. Full article
(This article belongs to the Special Issue Current Trends in Nanoscale Magnetism)
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