Special Issue "Electrophilic & Nucleophilic Substitution"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 May 2013).
Interests: pyrroles; aminopyrroles; electrophilic aromatic substitution by addition-elimination; electrophilic aromatic substitution; N-chlorination; inverse electron demand Diels-Alder reactions; S_N AR; tautomerism
In 1934, in a Chemical Society Chemical Reviews paper entitled “Principles of an electronic theory of organic reactions”, Ingold introduced the terms electrophilic and nucleophilic into chemistry. Since then they have become basic concepts used to explain electrophile-nucleophile combinations. Physical organic chemists have developed scales/equations to quantify these effects based on model reactions; electronic factors have been considered; more recently theoreticians have used density-functional theory (DFT) to create indices or descriptors of electrophilicity and nucleophilicity. This issue aims to bring together a representative sample of current experimental and theoretical work in this area.
Prof. Dr. Michael De Rosa
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access semimonthly journal published by MDPI.
- electrophilic substitution or addition
- nucleophilic substitution or addition
- electrophile-nucleophile combinations
- scales/indices of electrophilicity and nucleophilicity
- theoretical Studies