Special Issue "Microwave-mediated Chemistry"
Deadline for manuscript submissions: 30 April 2019
Microwave-mediated chemistry continues to have an impact on chemical synthesis, scale-up, medicinal chemistry, catalysis, material science and many other areas of science. Often, yields are improved and processes can be carried out in minutes compared to their thermal counterparts. Many processes can be carried out in batches or can be solvent-free.
It is a great pleasure to invite you to participate in show-casing your work in microwave-mediated chemistry.Prof. Dr. John Spencer
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- medicinal chemistry
- flow chemistry
- materials science
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Advantages of Green CuAAC Methodologies: Microwave and Solvent-less
Authors: Clayton J. Hull-Crew, Marissa N.Trujillo, Andrew D. Outlaw, Christopher M. Clements, Ashleigh A. Zeller, Loren J.Taylor, Kevin A. Stewart and Allen M. Schoffstall*
Affiliation: Department of Chemistry and Biochemistry, University of Colorado Colorado Springs (UCCS), Colorado Springs CO80918, United States
Abstract: Numerous modifications of the original conditions reported for successful copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) have added new choices when performing CuAAC click chemistry. Four different methods were chosen as being representative for comparison in terms of overall efficiency of the synthetic method, including time required for the synthesis and yield, ease of isolation and purity of the
1/H/-1,2,3-triazole product. The methods were those first reported (conventional heating), the microwave method, a method using a copper-carbene catalyst (solvent-less) and a method employing a CuI catalyst. Reactants for this study are non-fluorinated and fluorinated components. Results lead to a conclusion that a microwave method for the CuAAC reaction should be considered among others. The less general solvent-less method often gave comparable results.
Keywords: organic synthesis, triazole, copper-catalyzed azide-alkyne cycloaddition (CuAAC), microwave heating, solvent-less reaction, green chemistry