Isolation and Structure Elucidation of Bioactive Compounds (Dedicated to the memory of the late Professor Charles D. Hufford)

Dear Colleagues,

Throughout the history of mankind, plants have played an indispensible role for the benefit of human health. From ancient folk medicine to modern drugs, dietary supplements and even agrochemicals, the chemistry of plant constituents has become more important for us in understanding life threatening human diseases and chemoprevention practices. The absence of curative drugs in cognitive health has led the worlds aging population toward traditional medicine-based supplements. Isolation and structure determination of these diverse bioactive molecules that only nature can produce, has become a key area for generating new scaffolds for various biological explorations in medicinal chemistry. This is an area currently depleting rapidly due to the disappearance of natural resources. For these reasons, we think it is appropriate to document some recent research in this endeavor.

We wish to dedicate this Special Issue to the memory of the late Professor Charles D. Hufford, a true research pioneer in the fields of natural products and pharmacognosy, who has made immense contributions to the field. Advances in the isolation and structure elucidation, using NMR technology of bioactive compounds, especially secondary plant metabolites, was a passion of Professor Hufford, and therefore, this Special Issue of the journal Molecules has been dedicated to his memory.

Prof. Dr. Muhammad Ilias
Dr. Charles L. Cantrell
Guest Editors

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