The Therapeutic Potential of Natural and Synthetic Anti-Inflammatories

Dear Colleagues,

Inflammation is a fundamental biological response to injury or infection, but when dysregulated, it can lead to chronic diseases such as arthritis, cardiovascular conditions, neurodegenerative disorders, and cancer. As the global burden of these diseases rises, so does the urgency to develop more effective and safer anti-inflammatory therapies. This Special Issue, “The Therapeutic Potential of Natural and Synthetic Anti-Inflammatories”, aims to spotlight recent advances in the discovery, development, and mechanistic understanding of both plant-derived and chemically synthesized anti-inflammatory compounds.

From bioactive phytochemicals to rationally designed molecules, the contributions in this Special Issue explore innovative strategies for modulating inflammatory pathways, improving drug selectivity, and reducing side effects. Emphasis is placed on translational research that bridges laboratory findings with clinical relevance. By uniting diverse approaches—from ethnopharmacology to molecular pharmacology—this edition invites researchers to reimagine inflammation control through interdisciplinary perspectives.

We invite readers to engage with this timely collection of articles and consider the evolving landscape of inflammation research and therapy.

Prof. Dr. Alisson Macário De Oliveira
Prof. Dr. Patrícia Maria Guedes Paiva
Guest Editors

Dr. Wendeo Kennedy Costa
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.