Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes

Dear Colleagues,

In May 2017, the ‘’Medicinal Chemistry’’ section of Molecules launched the series of Editorials Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes [1], which are published on a biannual basis. In these editorials, the section Editorial Board highlight in brief reports (of about one hundred words) selected recent articles from all publishers that describe groundbreaking findings, such as the discovery of novel drug targets and mechanisms of action or novel classes of drugs, which are expected to inspire future medicinal chemistry endeavors devoted to addressing prime unmet medical needs. Encouraged by the acceptance of this series of editorials, and in a further effort to improve our services for the medicinal chemistry community, we have decided to go beyond the brief highlights of the editorials by setting up a parallel topical collection, with the same name. The topical collection will consist of a series of Special Issues to be published annually, which will collect provoking Comments, Opinions, Perspectives, Reviews, and Original Research Articles that focus on the hot topics that have been highlighted in the two previously published editorials. These regular longer-form contributions will elaborate on the background of the hot topics selected in the editorials, to better outline the high potential of these works and shape future medicinal chemistry and drug discovery strategies. Thus, this topical collection will be a unique platform to increase awareness, in a timely manner, of the current greatest challenges and most promising discoveries in the medicinal chemistry and drug discovery field.

1. Muñoz-Torrero, D.; Mangoni, A. A.; Guillou, C.; Collina, S.; Vanden Eynde, J. J.; Rautio, J.; Keseru, G. M.; Hulme, C.; Chibale, K.; Luque, F. J.; Karaman, R.; Gütschow, M.; Liu, H.; Ragno, R. Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes. Molecules 2017, 22, 743.

Prof. Dr. Diego Muñoz-Torrero
Dr. Cristobal De Los Rios
Collection Editors

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