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Isolation, Identification, and Applications of Bioactive Compounds from Marine Plants

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (30 April 2025) | Viewed by 5312

Special Issue Editor


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Guest Editor
1. Biochemistry Unit, Department of Biology, University of Pisa, 56123 Pisa, Italy
2. Interdepartmental Research Center Nutrafood “Nutraceuticals and Food for Health”, University of Pisa, 56124 Pisa, Italy
Interests: enzyme kinetics; protein purification; enzyme modulatiom; drug discovery; metabolite extraction
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Special Issue Information

Dear Colleagues,

Marine plants are plants adapted to grow under the sea or ocean. There are thousands of different types of marine plants growing in the world’s oceans and seas and their adaptation to the aquatic environment is variable. There are marine plants that live totally submerged, while others have large emerging parts. These plants include algae and vascular plant species. Marine plants play fundamental roles in marine ecosystem by keeping water oxygenated, providing a food source for aquatic life, and protecting smaller marine animals from predators.

Like terrestrial plant, marine plants could be considered as a prominent source of biofuels, nonfuels, and bioactive compounds ascertained for various pharmacological utilizations. In particular, considering their unique aquatic environment and rich biodiversity, marine plants could be considered a useful source of structurally novel and biologically active metabolites. This Special Issue will include reviews and research articles focused on functional and innovative technologies to extract and isolate metabolites from marine plants capable of effectively interacting with a therapeutic target in order to develop a drug suitable for clinical trials. Please send me an abstract prior to submission to make sure that your work falls within the scope of this Special Issue.

Dr. Francesco Balestri
Guest Editor

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Keywords

  • marine plant
  • bioactive compounds
  • metabolite purification
  • drug discovery
  • therapeutic target

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Published Papers (2 papers)

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Research

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16 pages, 1130 KiB  
Article
A Comparison of Methods for Assessing the Antioxidant Expression in Posidonia oceanica (L.) Delile
by Debora Fontanini, Fabio Bulleri, Chiara Ravaglioli and Antonella Capocchi
Molecules 2025, 30(8), 1828; https://doi.org/10.3390/molecules30081828 - 18 Apr 2025
Viewed by 147
Abstract
Non-enzymatic antioxidants, such as polyphenols, can counteract free radicals and other potentially toxic oxidants produced by marine plants exposed to stress. In this study, we assessed different methods for measuring antioxidant capacities and condensed tannins in the seagrass Posidonia oceanica (L.) Delile. Two [...] Read more.
Non-enzymatic antioxidants, such as polyphenols, can counteract free radicals and other potentially toxic oxidants produced by marine plants exposed to stress. In this study, we assessed different methods for measuring antioxidant capacities and condensed tannins in the seagrass Posidonia oceanica (L.) Delile. Two polyphenol extraction methods, direct and sequential, were compared to determine their efficiencies. Condensed tannins were assayed directly on leaf flour using a modified HCl-butanol-acetone-iron reagent method. Total antioxidant capacities were assayed with the ABTS, CUPRAC, and ORAC methods, both on extracts and on powdered samples (QUENCHER). The direct assays showed higher sensitivity compared to their in-solution counterparts. Our results indicate that in-depth measurement of antioxidant compounds and capacities can be achieved by direct assays on P. oceanica powder samples, and these data can be used to assess changes in the plant biochemistry due to the exposure to varying biotic and abiotic conditions. Full article
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Review

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24 pages, 1264 KiB  
Review
Spirulina—An Invaluable Source of Macro- and Micronutrients with Broad Biological Activity and Application Potential
by Izabela Podgórska-Kryszczuk
Molecules 2024, 29(22), 5387; https://doi.org/10.3390/molecules29225387 - 15 Nov 2024
Cited by 3 | Viewed by 4576
Abstract
With population growth expected in the near future and the planet’s limited resources, alternative food sources are already being looked for. In this context, spirulina is called the food of the future due to its rich nutritional composition. This blue–green alga is primarily [...] Read more.
With population growth expected in the near future and the planet’s limited resources, alternative food sources are already being looked for. In this context, spirulina is called the food of the future due to its rich nutritional composition. This blue–green alga is primarily a valuable source of protein (55–70%) containing all essential amino acids. In its composition, it also contains unsaturated fatty acids, minerals, vitamins, and pigments, including the valuable protein–pigment complex—phycocyanin. Due to its high content of complete protein and minerals such as iron and calcium, it is an excellent addition to diets, especially those of vegans and vegetarians. Despite several limitations to the use of spirulina, including its distinctive marine flavour, low consumer awareness, or relatively high price, scientists are attempting to enrich many food products with the microalga. This is supported not only by the improved nutritional composition of the fortified product but also by spirulina’s impact on sustainable food production. Therefore, this review aims to create consumer attention by presenting spirulina as a valuable and sustainable food source with health-promoting potential and great future significance. Full article
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