Polymer-Based Microfluidics

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 3296

Special Issue Editors


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Guest Editor
School of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
Interests: manufacturing of microfluidic systems; microfluidic technology with life sciences and analytical chemistry
Special Issues, Collections and Topics in MDPI journals
Department of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China
Interests: microfluidics; fluid mechanics; wettability; biomimetics; micro/nanorobots
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, Jiangsu, China
Interests: polymer microfluidics; droplets; high-speed imaging

Special Issue Information

Dear Colleagues,

Early microfluidics usually used silicon or glass materials with fabrication methods inherited from the MEMS field; however, to lower the instrument and material costs, polymer materials have been widely used in the recent two decades. Both elastomers, such as PDMS, and thermoplastics, such as PMMA, COC, COP, and PS, are now used in polymer microfluidics with the advantages of being low-cost and easy-to-process as well as their widely available physical/chemical properties. Polymer-based microfluidic devices are also widely adopted in commercial POCT products and most flexible microfluidics are also polymer-based. Polymer-based microfluidics have been widely used in various applications including biomedical devices, soft robotics, and chemical synthesis.

In this Special Issue, we seek to invite the most up-to-date studies on a wide range of polymer microfluidics and their applications including, but not limited to, innovative polymer materials used in microfluidics; new fabrication/processing methods for polymer microfluidics; 3D printing approaches for polymer microfluidics; characterization of the performance of polymer materials in microfluidics; chemical resistance/biocompatibility of the polymer materials used in microfluidics; surface modification methods for polymer microfluidics; integration of polymer parts on the microfludics, such as integration of membranes as enrichment part on microfluidics, polymer-based flexible substrate microfluidics for wearable applications, polymer-based photonics for the detections; and flexible microfluidics and polymer microfluidics applications in various fields.

Prof. Dr. Yiqiang Fan
Dr. Pingan Zhu
Dr. Jiaming Zhang
Guest Editors

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Keywords

  • microfluidics
  • polymer microfluidics
  • PDMS
  • PMMA
  • COC
  • microfabrication
  • flexible microfluidics
  • wearable devices
  • soft robotics

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Published Papers (1 paper)

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Research

14 pages, 2563 KiB  
Article
One-Step Fabrication of Microfluidic Channels in Polydimethylsiloxane: Influence of Laser Power on Channel Formation
by Seong-Yeop Kim, Han-Byeol Son and Hyo-Ryoung Lim
Micromachines 2025, 16(3), 282; https://doi.org/10.3390/mi16030282 - 28 Feb 2025
Viewed by 1765
Abstract
Recent advancements in microfluidic technologies have revolutionized their applications, particularly in drug monitoring, continuous biochemical analysis, and real-time physiological assessments. However, the fabrication of microfluidic devices with precise flow control remains constrained by either cost-prohibitive photolithography processes or limited-precision 3D printing techniques. In [...] Read more.
Recent advancements in microfluidic technologies have revolutionized their applications, particularly in drug monitoring, continuous biochemical analysis, and real-time physiological assessments. However, the fabrication of microfluidic devices with precise flow control remains constrained by either cost-prohibitive photolithography processes or limited-precision 3D printing techniques. In this study, we propose a one-step fabrication method employing picosecond laser processing to directly create microfluidic channels in (PDMS). This method achieves micron-scale channel precision while significantly simplifying the fabrication process and reducing costs. This approach eliminates the need for additional encapsulation steps, further reducing contamination risks and improving production scalability. These findings highlight the potential of this fabrication method to advance next-generation wearable biochemical devices and personalized healthcare technologies. Full article
(This article belongs to the Special Issue Polymer-Based Microfluidics)
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